rs6882716

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0215 (6457/29940,GnomAD)
G==0226 (6594/29118,TOPMED)
G==0399 (1996/5008,1000G)
G==0099 (383/3854,ALSPAC)
G==0097 (358/3708,TWINSUK)
chr5:10797774 (GRCh38.p7) (5p15.2)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
31 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.10797774G>A
GRCh37.p13 chr 5NC_000005.9:g.10797886G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.348A=0.652
1000GenomesAmericanSub694G=0.290A=0.710
1000GenomesEast AsianSub1008G=0.846A=0.154
1000GenomesEuropeSub1006G=0.106A=0.894
1000GenomesGlobalStudy-wide5008G=0.399A=0.601
1000GenomesSouth AsianSub978G=0.380A=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.099A=0.901
The Genome Aggregation DatabaseAfricanSub8714G=0.306A=0.694
The Genome Aggregation DatabaseAmericanSub836G=0.350A=0.650
The Genome Aggregation DatabaseEast AsianSub1614G=0.887A=0.113
The Genome Aggregation DatabaseEuropeSub18476G=0.109A=0.890
The Genome Aggregation DatabaseGlobalStudy-wide29940G=0.215A=0.784
The Genome Aggregation DatabaseOtherSub300G=0.170A=0.830
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.226A=0.773
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.097A=0.903
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs68827160.000002alcohol consumption (maxi-drinks)24277619
rs68827162.00E-06alcohol drinking24277619

eQTL of rs6882716 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6882716 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr51075668410757167E068-40719
chr51075721310757446E068-40440
chr51078862110788704E068-9182
chr51078894110789641E068-8245
chr51075961910759704E069-38182
chr51075979110759847E069-38039
chr51078862110788704E069-9182
chr51078894110789641E069-8245
chr51075721310757446E070-40440
chr51075767810757899E070-39987
chr51078862110788704E071-9182
chr51078862110788704E072-9182
chr51078894110789641E072-8245
chr51078894110789641E074-8245
chr51075223310752303E081-45583
chr51075268210752809E081-45077
chr51075328710753337E081-44549
chr51075339410753602E081-44284
chr51075374410753976E081-43910
chr51075491110754961E081-42925
chr51075668410757167E081-40719
chr51075721310757446E081-40440
chr51075767810757899E081-39987
chr51075829810758651E081-39235
chr51075868810758916E081-38970
chr51075268210752809E082-45077
chr51075328710753337E082-44549
chr51075339410753602E082-44284
chr51075374410753976E082-43910
chr51075668410757167E082-40719
chr51075721310757446E082-40440








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr51076014010763394E067-34492
chr51076014010763394E068-34492
chr51076014010763394E069-34492
chr51076014010763394E070-34492
chr51076014010763394E071-34492
chr51076014010763394E072-34492
chr51076014010763394E073-34492
chr51076014010763394E074-34492
chr51076014010763394E082-34492