SNP Detail Info-rs6891749

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0066 (1984/29960,GnomAD)
A=0070 (2056/29118,TOPMED)
A=0053 (265/5008,1000G)
A=0050 (193/3854,ALSPAC)
A=0052 (191/3708,TWINSUK)

Position: chr5:107803280 (GRCh38.p7) (5q21.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 7 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.107803280G>A
GRCh37.p13 chr 5	NC_000005.9:g.107138981G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.866	A=0.134
1000Genomes	American	Sub	694	G=0.970	A=0.030
1000Genomes	East Asian	Sub	1008	G=0.983	A=0.017
1000Genomes	Europe	Sub	1006	G=0.958	A=0.042
1000Genomes	Global	Study-wide	5008	G=0.947	A=0.053
1000Genomes	South Asian	Sub	978	G=0.990	A=0.010
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.950	A=0.050
The Genome Aggregation Database	African	Sub	8718	G=0.887	A=0.113
The Genome Aggregation Database	American	Sub	836	G=0.970	A=0.030
The Genome Aggregation Database	East Asian	Sub	1620	G=0.978	A=0.022
The Genome Aggregation Database	Europe	Sub	18484	G=0.949	A=0.050
The Genome Aggregation Database	Global	Study-wide	29960	G=0.933	A=0.066
The Genome Aggregation Database	Other	Sub	302	G=0.990	A=0.010
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.929	A=0.070
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.948	A=0.052

PMID	Title	Author	Journal
21314694	Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.	Kendler KS	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs6891749	0.000714	alcohol dependence	21314694

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr5	107140779	107141147	E070	1798
chr5	107141604	107141709	E070	2623
chr5	107142042	107142355	E070	3061
chr5	107144282	107144943	E070	5301
chr5	107170392	107170499	E081	31411
chr5	107170668	107171289	E081	31687
chr5	107171405	107171455	E081	32424

rs6891749