rs6891749

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0066 (1984/29960,GnomAD)
A=0070 (2056/29118,TOPMED)
A=0053 (265/5008,1000G)
A=0050 (193/3854,ALSPAC)
A=0052 (191/3708,TWINSUK)
chr5:107803280 (GRCh38.p7) (5q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
7 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.107803280G>A
GRCh37.p13 chr 5NC_000005.9:g.107138981G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.866A=0.134
1000GenomesAmericanSub694G=0.970A=0.030
1000GenomesEast AsianSub1008G=0.983A=0.017
1000GenomesEuropeSub1006G=0.958A=0.042
1000GenomesGlobalStudy-wide5008G=0.947A=0.053
1000GenomesSouth AsianSub978G=0.990A=0.010
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.950A=0.050
The Genome Aggregation DatabaseAfricanSub8718G=0.887A=0.113
The Genome Aggregation DatabaseAmericanSub836G=0.970A=0.030
The Genome Aggregation DatabaseEast AsianSub1620G=0.978A=0.022
The Genome Aggregation DatabaseEuropeSub18484G=0.949A=0.050
The Genome Aggregation DatabaseGlobalStudy-wide29960G=0.933A=0.066
The Genome Aggregation DatabaseOtherSub302G=0.990A=0.010
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.929A=0.070
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.948A=0.052
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs68917490.000714alcohol dependence21314694

eQTL of rs6891749 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6891749 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5107140779107141147E0701798
chr5107141604107141709E0702623
chr5107142042107142355E0703061
chr5107144282107144943E0705301
chr5107170392107170499E08131411
chr5107170668107171289E08131687
chr5107171405107171455E08132424