rs6895323

Homo sapiens
G>C
LOC101927421 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0343 (10268/29872,GnomAD)
G==0358 (10429/29118,TOPMED)
G==0377 (1889/5008,1000G)
G==0277 (1069/3854,ALSPAC)
G==0281 (1043/3708,TWINSUK)
chr5:125193762 (GRCh38.p7) (5q23.2)
CD
GWASdb2
1   publication(s)
See rs on genome
112 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.125193762G>C
GRCh37.p13 chr 5NC_000005.9:g.124529455G>C

Gene: LOC101927421, uncharacterized LOC101927421(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC101927421 transcriptNR_109882.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.497C=0.503
1000GenomesAmericanSub694G=0.400C=0.600
1000GenomesEast AsianSub1008G=0.470C=0.530
1000GenomesEuropeSub1006G=0.252C=0.748
1000GenomesGlobalStudy-wide5008G=0.377C=0.623
1000GenomesSouth AsianSub978G=0.230C=0.770
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.277C=0.723
The Genome Aggregation DatabaseAfricanSub8694G=0.477C=0.523
The Genome Aggregation DatabaseAmericanSub836G=0.420C=0.580
The Genome Aggregation DatabaseEast AsianSub1610G=0.443C=0.557
The Genome Aggregation DatabaseEuropeSub18430G=0.270C=0.729
The Genome Aggregation DatabaseGlobalStudy-wide29872G=0.343C=0.656
The Genome Aggregation DatabaseOtherSub302G=0.200C=0.800
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.358C=0.641
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.281C=0.719
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs68953230.0000043cocaine dependence,AA23958962
rs68953230.0000429cocaine dependence23958962

eQTL of rs6895323 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6895323 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5124486690124487119E067-42336
chr5124487380124487471E067-41984
chr5124487852124487932E067-41523
chr5124488597124488806E067-40649
chr5124488860124489208E067-40247
chr5124532177124532857E0672722
chr5124532933124533325E0673478
chr5124533739124533789E0674284
chr5124534101124534681E0674646
chr5124572727124573035E06743272
chr5124487380124487471E068-41984
chr5124487852124487932E068-41523
chr5124488597124488806E068-40649
chr5124532177124532857E0682722
chr5124534101124534681E0684646
chr5124537279124537392E0687824
chr5124558638124558874E06829183
chr5124571706124572030E06842251
chr5124572104124572170E06842649
chr5124572375124572468E06842920
chr5124572727124573035E06843272
chr5124485666124485963E069-43492
chr5124486002124486484E069-42971
chr5124486690124487119E069-42336
chr5124487380124487471E069-41984
chr5124532933124533325E0693478
chr5124533739124533789E0694284
chr5124534101124534681E0694646
chr5124534917124534967E0695462
chr5124534999124535087E0695544
chr5124535125124535207E0695670
chr5124572727124573035E06943272
chr5124486690124487119E070-42336
chr5124487380124487471E070-41984
chr5124532177124532857E0702722
chr5124532933124533325E0703478
chr5124533739124533789E0704284
chr5124534101124534681E0704646
chr5124534917124534967E0705462
chr5124534999124535087E0705544
chr5124535125124535207E0705670
chr5124535815124535881E0706360
chr5124537279124537392E0707824
chr5124537443124537560E0707988
chr5124484708124485602E071-43853
chr5124487380124487471E071-41984
chr5124487852124487932E071-41523
chr5124488597124488806E071-40649
chr5124532177124532857E0712722
chr5124532933124533325E0713478
chr5124533739124533789E0714284
chr5124534101124534681E0714646
chr5124534917124534967E0715462
chr5124534999124535087E0715544
chr5124535125124535207E0715670
chr5124572375124572468E07142920
chr5124572727124573035E07143272
chr5124485666124485963E072-43492
chr5124486690124487119E072-42336
chr5124487380124487471E072-41984
chr5124487852124487932E072-41523
chr5124532177124532857E0722722
chr5124534101124534681E0724646
chr5124572727124573035E07243272
chr5124484708124485602E074-43853
chr5124485666124485963E074-43492
chr5124486002124486484E074-42971
chr5124486690124487119E074-42336
chr5124487380124487471E074-41984
chr5124487852124487932E074-41523
chr5124488597124488806E074-40649
chr5124532177124532857E0742722
chr5124532933124533325E0743478
chr5124533739124533789E0744284
chr5124534101124534681E0744646
chr5124534917124534967E0745462
chr5124534999124535087E0745544
chr5124535125124535207E0745670
chr5124537279124537392E0747824
chr5124537443124537560E0747988
chr5124558520124558597E07429065
chr5124558638124558874E07429183
chr5124568323124569000E07438868
chr5124572375124572468E07442920
chr5124572727124573035E07443272
chr5124515218124515607E081-13848
chr5124531552124531826E0812097
chr5124532177124532857E0812722
chr5124532933124533325E0813478
chr5124533739124533789E0814284
chr5124534101124534681E0814646
chr5124534917124534967E0815462
chr5124534999124535087E0815544
chr5124535125124535207E0815670
chr5124535815124535881E0816360
chr5124571706124572030E08142251
chr5124572104124572170E08142649
chr5124572375124572468E08142920
chr5124572727124573035E08143272
chr5124532933124533325E0823478
chr5124533739124533789E0824284
chr5124534101124534681E0824646
chr5124534917124534967E0825462
chr5124534999124535087E0825544
chr5124535125124535207E0825670
chr5124535815124535881E0826360
chr5124537279124537392E0827824
chr5124537443124537560E0827988
chr5124571706124572030E08242251
chr5124572104124572170E08242649
chr5124572375124572468E08242920
chr5124572727124573035E08243272