SNP Detail Info-rs6899567

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0141 (4248/29954,GnomAD)
A=0184 (5358/29118,TOPMED)
A=0129 (644/5008,1000G)
A=0064 (247/3854,ALSPAC)
A=0058 (215/3708,TWINSUK)

Position: chr6:212595 (GRCh38.p7) (6p25.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 2 publication(s)

Genomic View: See rs on genome

Enhancer: 5 Enhancers around

Promoter: 7 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 6	NC_000006.12:g.212595G>A
GRCh37.p13 chr 6	NC_000006.11:g.212595G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.601	A=0.399
1000Genomes	American	Sub	694	G=0.940	A=0.060
1000Genomes	East Asian	Sub	1008	G=1.000	A=0.000
1000Genomes	Europe	Sub	1006	G=0.941	A=0.059
1000Genomes	Global	Study-wide	5008	G=0.871	A=0.129
1000Genomes	South Asian	Sub	978	G=0.980	A=0.020
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.936	A=0.064
The Genome Aggregation Database	African	Sub	8706	G=0.658	A=0.342
The Genome Aggregation Database	American	Sub	838	G=0.950	A=0.050
The Genome Aggregation Database	East Asian	Sub	1622	G=1.000	A=0.000
The Genome Aggregation Database	Europe	Sub	18486	G=0.934	A=0.065
The Genome Aggregation Database	Global	Study-wide	29954	G=0.858	A=0.141
The Genome Aggregation Database	Other	Sub	302	G=0.940	A=0.060
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.816	A=0.184
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.942	A=0.058

PMID	Title	Author	Journal
19725835	Binomial mixture model-based association tests under genetic heterogeneity.	Zhou H	Ann Hum Genet
22481050	Genetic influences on craving for alcohol.	Agrawal A	Addict Behav

SNP ID	p-value	Traits	Study
rs6899567	3.76E-05	alcohol craving with or without dependence	22481050

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr6	188637	189287	E069	-23308
chr6	227391	227566	E069	14796
chr6	211994	212056	E070	-539
chr6	211994	212056	E072	-539
chr6	211994	212056	E073	-539

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr6	235942	236383	E067	23347
chr6	235942	236383	E068	23347
chr6	235942	236383	E069	23347
chr6	235942	236383	E071	23347
chr6	235942	236383	E072	23347
chr6	235942	236383	E073	23347
chr6	235942	236383	E074	23347

rs6899567