SNP Detail Info-rs6902771

Molecule type	Change	Amino acid[Codon]	SO Term
ESR1 transcript variant 1	NM_000125.3:c.	N/A	Intron Variant
ESR1 transcript variant 2	NM_001122740.1:c.	N/A	Intron Variant
ESR1 transcript variant 3	NM_001122741.1:c.	N/A	Intron Variant
ESR1 transcript variant 4	NM_001122742.1:c.	N/A	Intron Variant
ESR1 transcript variant 5	NM_001291230.1:c.	N/A	Intron Variant
ESR1 transcript variant 6	NM_001291241.1:c.	N/A	Intron Variant
ESR1 transcript variant X11	XM_006715374.3:c.	N/A	Intron Variant
ESR1 transcript variant X12	XM_006715375.3:c.	N/A	Intron Variant
ESR1 transcript variant X1	XM_011535543.2:c.	N/A	Intron Variant
ESR1 transcript variant X7	XM_011535544.2:c.	N/A	Intron Variant
ESR1 transcript variant X9	XM_011535545.2:c.	N/A	Intron Variant
ESR1 transcript variant X10	XM_011535547.2:c.	N/A	Intron Variant
ESR1 transcript variant X2	XM_017010376.1:c.	N/A	Intron Variant
ESR1 transcript variant X3	XM_017010377.1:c.	N/A	Intron Variant
ESR1 transcript variant X4	XM_017010378.1:c.	N/A	Intron Variant
ESR1 transcript variant X5	XM_017010379.1:c.	N/A	Intron Variant
ESR1 transcript variant X6	XM_017010380.1:c.	N/A	Intron Variant
ESR1 transcript variant X8	XM_017010381.1:c.	N/A	Intron Variant
ESR1 transcript variant X13	XM_017010382.1:c.	N/A	Intron Variant
ESR1 transcript variant X15	XM_011535549.2:c.	N/A	Genic Upstream Transcript Variant
ESR1 transcript variant X16	XM_017010383.1:c.	N/A	Genic Upstream Transcript Variant
ESR1 transcript variant X14	XR_001743222.1:n.	N/A	Intron Variant
ESR1 transcript variant X15	XR_001743223.1:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.498	T=0.502
1000Genomes	American	Sub	694	C=0.660	T=0.340
1000Genomes	East Asian	Sub	1008	C=0.599	T=0.401
1000Genomes	Europe	Sub	1006	C=0.573	T=0.427
1000Genomes	Global	Study-wide	5008	C=0.577	T=0.423
1000Genomes	South Asian	Sub	978	C=0.610	T=0.390
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.544	T=0.456
The Genome Aggregation Database	African	Sub	8692	C=0.518	T=0.482
The Genome Aggregation Database	American	Sub	838	C=0.680	T=0.320
The Genome Aggregation Database	East Asian	Sub	1614	C=0.599	T=0.401
The Genome Aggregation Database	Europe	Sub	18466	C=0.539	T=0.460
The Genome Aggregation Database	Global	Study-wide	29912	C=0.540	T=0.459
The Genome Aggregation Database	Other	Sub	302	C=0.550	T=0.450
Trans-Omics for Precision Medicine	Global	Study-wide	29118	C=0.547	T=0.452
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.547	T=0.453

PMID	Title	Author	Journal
18305958	Comprehensive evaluation of the estrogen receptor alpha gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American population.	Keene KL	Hum Genet
22259677	Association between ESR1 rs1884051 polymorphism and dietary total energy and plant protein intake on obesity in Korean men.	Doo M	Nutr Res Pract
20615892	Inherited variations in AR, ESR1, and ESR2 genes are not associated with prostate cancer aggressiveness or with efficacy of androgen deprivation therapy.	Sun T	Cancer Epidemiol Biomarkers Prev
24149131	Candidate gene analysis in israeli soldiers with stress fractures.	Yanovich R	J Sports Sci Med
19581569	Genome-wide association study of alcohol dependence.	Treutlein J	Arch Gen Psychiatry
18053221	Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis--a cohort study.	Nilsson M	BMC Med Genet
20148360	Genetic variation in sex-steroid receptors and synthesizing enzymes and colorectal cancer risk in women.	Lin J	Cancer Causes Control

SNP ID	p-value	Traits	Study
rs6902771	8E-06	alcohol dependence	19581569

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr6	152174582	152174632	E070	16701
chr6	152174706	152174826	E070	16825

rs6902771