rs6903616

Homo sapiens
C>T
MOXD1 : 3 Prime UTR Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0130 (3897/29932,GnomAD)
T=0151 (4421/29118,TOPMED)
T=0147 (734/5008,1000G)
T=0047 (181/3854,ALSPAC)
T=0054 (201/3708,TWINSUK)
chr6:132296330 (GRCh38.p7) (6q23.2)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Enhancers around
8 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.132296330C>T
GRCh37.p13 chr 6NC_000006.11:g.132617469C>T

Gene: MOXD1, monooxygenase DBH like 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
MOXD1 transcriptNM_015529.3:c.N/A3 Prime UTR Variant
MOXD1 transcript variant X1XM_017010714.1:c.N/A3 Prime UTR Variant
MOXD1 transcript variant X2XM_017010715.1:c.N/A3 Prime UTR Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.669T=0.331
1000GenomesAmericanSub694C=0.960T=0.040
1000GenomesEast AsianSub1008C=0.913T=0.087
1000GenomesEuropeSub1006C=0.940T=0.060
1000GenomesGlobalStudy-wide5008C=0.853T=0.147
1000GenomesSouth AsianSub978C=0.880T=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.953T=0.047
The Genome Aggregation DatabaseAfricanSub8704C=0.718T=0.282
The Genome Aggregation DatabaseAmericanSub838C=0.960T=0.040
The Genome Aggregation DatabaseEast AsianSub1602C=0.902T=0.098
The Genome Aggregation DatabaseEuropeSub18486C=0.933T=0.066
The Genome Aggregation DatabaseGlobalStudy-wide29932C=0.869T=0.130
The Genome Aggregation DatabaseOtherSub302C=0.960T=0.040
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.848T=0.151
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.946T=0.054
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs69036160.00068alcohol dependence20201924

eQTL of rs6903616 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6903616 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6132601237132601297E068-16172
chr6132619587132619737E0692118
chr6132618451132618501E071982
chr6132601237132601297E072-16172
chr6132598988132599144E081-18325
chr6132598988132599144E082-18325
chr6132610790132610905E082-6564
chr6132611046132611145E082-6324






Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr6132600698132601199E067-16270
chr6132600698132601199E068-16270
chr6132600698132601199E069-16270
chr6132600698132601199E070-16270
chr6132600698132601199E071-16270
chr6132600698132601199E072-16270
chr6132600698132601199E074-16270
chr6132600698132601199E082-16270