rs6930781

Homo sapiens
A>C / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
C=0432 (12936/29904,GnomAD)
A==0498 (14527/29118,TOPMED)
C=0340 (1705/5008,1000G)
C=0398 (1533/3854,ALSPAC)
C=0394 (1461/3708,TWINSUK)
chr6:110006481 (GRCh38.p7) (6q21)
AD
GWASCatalog
1   publication(s)
See rs on genome
8 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.110006481A>C
GRCh38.p7 chr 6NC_000006.12:g.110006481A>T
GRCh37.p13 chr 6NC_000006.11:g.110327684A>C
GRCh37.p13 chr 6NC_000006.11:g.110327684A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.362C=0.638
1000GenomesAmericanSub694A=0.660C=0.340
1000GenomesEast AsianSub1008A=0.986C=0.014
1000GenomesEuropeSub1006A=0.607C=0.393
1000GenomesGlobalStudy-wide5008A=0.660C=0.340
1000GenomesSouth AsianSub978A=0.780C=0.220
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.602C=0.398
The Genome Aggregation DatabaseAfricanSub8702A=0.385C=0.615
The Genome Aggregation DatabaseAmericanSub836A=0.660C=0.340
The Genome Aggregation DatabaseEast AsianSub1618A=0.982C=0.018
The Genome Aggregation DatabaseEuropeSub18446A=0.610C=0.389
The Genome Aggregation DatabaseGlobalStudy-wide29904A=0.567C=0.432
The Genome Aggregation DatabaseOtherSub302A=0.690C=0.310
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.498C=0.501
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.606C=0.394
PMID Title Author Journal
29071344Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Zhou HJAMA Psychiatry

P-Value

SNP ID p-value Traits Study
rs69307813E-06alcohol dependence29071344

eQTL of rs6930781 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6930781 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr69188126691881382E070-37384
chr69188155491881743E070-37023
chr69188187491881968E070-36798
chr69188201391882418E070-36348
chr69188296391883075E070-35691
chr69188312991883208E070-35558
chr69188155491881743E081-37023
chr69188187491881968E081-36798