rs6940938

Homo sapiens
G>C
LOC105375040 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0324 (9705/29876,GnomAD)
C=0365 (10643/29118,TOPMED)
C=0307 (1537/5008,1000G)
C=0236 (911/3854,ALSPAC)
C=0227 (840/3708,TWINSUK)
chr6:37340818 (GRCh38.p7) (6p21.2)
ND
GWASdb2
1   publication(s)
See rs on genome
112 Enhancers around
18 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.37340818G>C
GRCh37.p13 chr 6NC_000006.11:g.37308594G>C

Gene: LOC105375040, uncharacterized LOC105375040(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105375040 transcriptXR_926762.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.437C=0.563
1000GenomesAmericanSub694G=0.700C=0.300
1000GenomesEast AsianSub1008G=0.865C=0.135
1000GenomesEuropeSub1006G=0.742C=0.258
1000GenomesGlobalStudy-wide5008G=0.693C=0.307
1000GenomesSouth AsianSub978G=0.800C=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.764C=0.236
The Genome Aggregation DatabaseAfricanSub8678G=0.497C=0.503
The Genome Aggregation DatabaseAmericanSub836G=0.670C=0.330
The Genome Aggregation DatabaseEast AsianSub1622G=0.881C=0.119
The Genome Aggregation DatabaseEuropeSub18438G=0.739C=0.260
The Genome Aggregation DatabaseGlobalStudy-wide29876G=0.675C=0.324
The Genome Aggregation DatabaseOtherSub302G=0.780C=0.220
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.634C=0.365
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.773C=0.227
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs69409380.000425nicotine smoking19268276

eQTL of rs6940938 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6940938 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr63727544537275916E067-32678
chr63727596137276195E067-32399
chr63727623137276322E067-32272
chr63727635337276480E067-32114
chr63727949837279922E067-28672
chr63728375437283804E067-24790
chr63728394937284133E067-24461
chr63728510737285748E067-22846
chr63733687737336927E06728283
chr63733773837337901E06729144
chr63733805537338121E06729461
chr63733899637339141E06730402
chr63734177337341874E06733179
chr63734201137342152E06733417
chr63727544537275916E068-32678
chr63727596137276195E068-32399
chr63727623137276322E068-32272
chr63727635337276480E068-32114
chr63727694537277063E068-31531
chr63728394937284133E068-24461
chr63728510737285748E068-22846
chr63728774237288172E068-20422
chr63728840937288506E068-20088
chr63728855537288674E068-19920
chr63728897337289194E068-19400
chr63728951737289792E068-18802
chr63729196537292401E068-16193
chr63732401037324054E06815416
chr63733687737336927E06828283
chr63733773837337901E06829144
chr63733805537338121E06829461
chr63727596137276195E069-32399
chr63727623137276322E069-32272
chr63727635337276480E069-32114
chr63727949837279922E069-28672
chr63727998337280295E069-28299
chr63728510737285748E069-22846
chr63733687737336927E06928283
chr63733773837337901E06929144
chr63733805537338121E06929461
chr63733899637339141E06930402
chr63733948237339532E06930888
chr63733958137339631E06930987
chr63733964237339692E06931048
chr63727544537275916E070-32678
chr63727596137276195E070-32399
chr63727623137276322E070-32272
chr63727635337276480E070-32114
chr63729123137291934E070-16660
chr63734177337341874E07033179
chr63734201137342152E07033417
chr63727596137276195E071-32399
chr63727623137276322E071-32272
chr63727635337276480E071-32114
chr63727949837279922E071-28672
chr63728510737285748E071-22846
chr63728840937288506E071-20088
chr63728855537288674E071-19920
chr63728951737289792E071-18802
chr63733460437334674E07126010
chr63733773837337901E07129144
chr63733805537338121E07129461
chr63733899637339141E07130402
chr63734177337341874E07133179
chr63734201137342152E07133417
chr63727623137276322E072-32272
chr63727635337276480E072-32114
chr63727949837279922E072-28672
chr63727998337280295E072-28299
chr63728510737285748E072-22846
chr63729123137291934E072-16660
chr63733345137333589E07224857
chr63733362937333794E07225035
chr63733687737336927E07228283
chr63733773837337901E07229144
chr63733805537338121E07229461
chr63733948237339532E07230888
chr63728510737285748E073-22846
chr63732401037324054E07315416
chr63733773837337901E07329144
chr63733805537338121E07329461
chr63733899637339141E07330402
chr63733948237339532E07330888
chr63733958137339631E07330987
chr63733964237339692E07331048
chr63727596137276195E074-32399
chr63727623137276322E074-32272
chr63727635337276480E074-32114
chr63727949837279922E074-28672
chr63728510737285748E074-22846
chr63733687737336927E07428283
chr63733773837337901E07429144
chr63733805537338121E07429461
chr63733899637339141E07430402
chr63733948237339532E07430888
chr63733958137339631E07430987
chr63733964237339692E07431048
chr63734177337341874E07433179
chr63734201137342152E07433417
chr63727544537275916E081-32678
chr63727596137276195E081-32399
chr63727623137276322E081-32272
chr63727635337276480E081-32114
chr63727694537277063E081-31531
chr63728375437283804E081-24790
chr63728394937284133E081-24461
chr63727623137276322E082-32272
chr63727635337276480E082-32114
chr63727694537277063E082-31531
chr63729123137291934E082-16660
chr63729196537292401E082-16193
chr63732401037324054E08215416










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr63732115837321250E06712564
chr63732130337322855E06712709
chr63732115837321250E06812564
chr63732130337322855E06812709
chr63732115837321250E06912564
chr63732130337322855E06912709
chr63732130337322855E07012709
chr63732115837321250E07112564
chr63732130337322855E07112709
chr63732115837321250E07212564
chr63732130337322855E07212709
chr63732115837321250E07312564
chr63732130337322855E07312709
chr63732115837321250E07412564
chr63732130337322855E07412709
chr63732115837321250E08112564
chr63732130337322855E08112709
chr63732130337322855E08212709