rs6951271

Homo sapiens
A>C / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
A=0336 (10012/29786,GnomAD)
A=0293 (8532/29118,TOPMED)
A=0394 (1971/5008,1000G)
A=0398 (1532/3854,ALSPAC)
A=0400 (1485/3708,TWINSUK)
chr7:142726593 (GRCh38.p7) (7q34)
AD
GWASCatalog
1   publication(s)
See rs on genome
0 Enhancer around
19 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.142726593A>C
GRCh38.p7 chr 7NC_000007.14:g.142726593A>T
GRCh37.p13 chr 7NC_000007.13:g.142434446C>A
GRCh37.p13 chr 7NC_000007.13:g.142434446C>T
GRCh38.p7 chr 7 alt locus HSCHR7_2_CTG6NT_187562.1:g.729187A>C
GRCh38.p7 chr 7 alt locus HSCHR7_2_CTG6NT_187562.1:g.729187A>T
GRCh37.p13 chr 7 fix patch HG7_PATCHNW_003571040.1:g.909258A>C
GRCh37.p13 chr 7 fix patch HG7_PATCHNW_003571040.1:g.909258A>T
TRB genomic regionNG_001333.2:g.560253A>C
TRB genomic regionNG_001333.2:g.560253A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.850A==0.150
1000GenomesAmericanSub694C=0.760A==0.240
1000GenomesEast AsianSub1008C=0.392A==0.608
1000GenomesEuropeSub1006C=0.626A==0.374
1000GenomesGlobalStudy-wide5008C=0.606A==0.394
1000GenomesSouth AsianSub978C=0.370A==0.630
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.602A==0.398
The Genome Aggregation DatabaseAfricanSub8656C=0.845A==0.155
The Genome Aggregation DatabaseAmericanSub838C=0.750A==0.250
The Genome Aggregation DatabaseEast AsianSub1604C=0.329A==0.671
The Genome Aggregation DatabaseEuropeSub18388C=0.604A==0.395
The Genome Aggregation DatabaseGlobalStudy-wide29786C=0.663A==0.336
The Genome Aggregation DatabaseOtherSub300C=0.640A==0.360
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.707A==0.293
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.600A==0.400
PMID Title Author Journal
29460428Genomewide Association Study of Alcohol Dependence and Related Traits in a Thai Population.Gelernter JAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs69512716E-06alcohol consumption measurement29460428

eQTL of rs6951271 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6951271 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr75792771057927946E06810806
chr75792827757928392E06811373
chr75792873157928954E06811827
chr75792771057927946E06910806
chr75792814657928196E06911242
chr75792827757928392E06911373
chr75792852357928639E06911619
chr75792771057927946E07110806
chr75792814657928196E07111242
chr75792827757928392E07111373
chr75792852357928639E07111619
chr75792873157928954E07111827
chr75792771057927946E07410806
chr75792814657928196E07411242
chr75792827757928392E07411373
chr75792852357928639E07411619
chr75792873157928954E07411827
chr75792899557929097E07412091
chr75792913457929208E07412230