rs6955063

Homo sapiens
A>C
SLC37A3 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0160 (4803/29940,GnomAD)
C=0190 (5548/29118,TOPMED)
C=0180 (899/5008,1000G)
C=0101 (390/3854,ALSPAC)
C=0097 (359/3708,TWINSUK)
chr7:140377628 (GRCh38.p7) (7q34)
AD
GWASdb2
1   publication(s)
See rs on genome
83 Enhancers around
12 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.140377628A>C
GRCh37.p13 chr 7NC_000007.13:g.140077428A>C

Gene: SLC37A3, solute carrier family 37 member 3(minus strand)

Molecule type Change Amino acid[Codon] SO Term
SLC37A3 transcript variant 3NM_001287498.1:c.N/AIntron Variant
SLC37A3 transcript variant 2NM_032295.3:c.N/AIntron Variant
SLC37A3 transcript variant 1NM_207113.2:c.N/AIntron Variant
SLC37A3 transcript variant X2XM_011516626.2:c.N/AIntron Variant
SLC37A3 transcript variant X3XM_011516627.2:c.N/AIntron Variant
SLC37A3 transcript variant X1XM_017012712.1:c.N/AIntron Variant
SLC37A3 transcript variant X4XM_017012713.1:c.N/AIntron Variant
SLC37A3 transcript variant X5XM_017012714.1:c.N/AIntron Variant
SLC37A3 transcript variant X6XM_017012715.1:c.N/AIntron Variant
SLC37A3 transcript variant X7XM_017012716.1:c.N/AIntron Variant
SLC37A3 transcript variant X8XM_017012717.1:c.N/AIntron Variant
SLC37A3 transcript variant X10XM_017012718.1:c.N/AIntron Variant
SLC37A3 transcript variant X9XR_927543.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.687C=0.313
1000GenomesAmericanSub694A=0.910C=0.090
1000GenomesEast AsianSub1008A=0.891C=0.109
1000GenomesEuropeSub1006A=0.892C=0.108
1000GenomesGlobalStudy-wide5008A=0.820C=0.180
1000GenomesSouth AsianSub978A=0.790C=0.210
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.899C=0.101
The Genome Aggregation DatabaseAfricanSub8710A=0.700C=0.300
The Genome Aggregation DatabaseAmericanSub836A=0.920C=0.080
The Genome Aggregation DatabaseEast AsianSub1622A=0.906C=0.094
The Genome Aggregation DatabaseEuropeSub18472A=0.896C=0.103
The Genome Aggregation DatabaseGlobalStudy-wide29940A=0.839C=0.160
The Genome Aggregation DatabaseOtherSub300A=0.830C=0.170
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.809C=0.190
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.903C=0.097
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs69550630.00004alcohol dependence20201924
rs69550630.0000402alcoholismpha002892

eQTL of rs6955063 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6955063 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7140029703140029894E067-47534
chr7140030053140030188E067-47240
chr7140030328140030378E067-47050
chr7140030430140030843E067-46585
chr7140034102140034152E067-43276
chr7140034220140034264E067-43164
chr7140034267140034955E067-42473
chr7140035039140035217E067-42211
chr7140048981140049603E067-27825
chr7140029703140029894E068-47534
chr7140030053140030188E068-47240
chr7140030328140030378E068-47050
chr7140033344140033423E068-44005
chr7140033558140033650E068-43778
chr7140034102140034152E068-43276
chr7140034220140034264E068-43164
chr7140034267140034955E068-42473
chr7140035039140035217E068-42211
chr7140048009140048563E068-28865
chr7140058233140058889E068-18539
chr7140029703140029894E069-47534
chr7140030053140030188E069-47240
chr7140030328140030378E069-47050
chr7140033137140033281E069-44147
chr7140033344140033423E069-44005
chr7140033558140033650E069-43778
chr7140034102140034152E069-43276
chr7140034220140034264E069-43164
chr7140034267140034955E069-42473
chr7140035039140035217E069-42211
chr7140089813140089863E06912385
chr7140089993140090143E06912565
chr7140090194140090327E06912766
chr7140090331140091024E06912903
chr7140030430140030843E070-46585
chr7140031058140031186E070-46242
chr7140048981140049603E070-27825
chr7140029703140029894E071-47534
chr7140030053140030188E071-47240
chr7140030328140030378E071-47050
chr7140033137140033281E071-44147
chr7140033344140033423E071-44005
chr7140033558140033650E071-43778
chr7140034102140034152E071-43276
chr7140034220140034264E071-43164
chr7140034267140034955E071-42473
chr7140035039140035217E071-42211
chr7140035698140035752E071-41676
chr7140089662140089774E07112234
chr7140089813140089863E07112385
chr7140089993140090143E07112565
chr7140090194140090327E07112766
chr7140090331140091024E07112903
chr7140091040140091234E07113612
chr7140091518140091721E07114090
chr7140091738140091904E07114310
chr7140091923140092047E07114495
chr7140096233140096639E07118805
chr7140096710140096798E07119282
chr7140097126140097166E07119698
chr7140029703140029894E072-47534
chr7140034220140034264E072-43164
chr7140034267140034955E072-42473
chr7140035039140035217E072-42211
chr7140035698140035752E072-41676
chr7140029703140029894E073-47534
chr7140030053140030188E073-47240
chr7140030430140030843E073-46585
chr7140048981140049603E073-27825
chr7140085021140085065E0737593
chr7140085068140085300E0737640
chr7140030053140030188E074-47240
chr7140030328140030378E074-47050
chr7140034102140034152E074-43276
chr7140034220140034264E074-43164
chr7140034267140034955E074-42473
chr7140035698140035752E074-41676
chr7140048981140049603E074-27825
chr7140030328140030378E081-47050
chr7140096710140096798E08119282
chr7140030053140030188E082-47240
chr7140030328140030378E082-47050
chr7140030430140030843E082-46585










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr7140097350140099043E06719922
chr7140097350140099043E06819922
chr7140097350140099043E06919922
chr7140097246140097331E07019818
chr7140097350140099043E07019922
chr7140097350140099043E07119922
chr7140097350140099043E07219922
chr7140097350140099043E07319922
chr7140097350140099043E07419922
chr7140103457140104903E07426029
chr7140097246140097331E08219818
chr7140097350140099043E08219922