rs6970410

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0349 (10461/29938,GnomAD)
C==0330 (9625/29118,TOPMED)
C==0439 (2201/5008,1000G)
C==0374 (1440/3854,ALSPAC)
C==0382 (1415/3708,TWINSUK)
chr7:7116841 (GRCh38.p7) (7p22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
10 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.7116841C>T
GRCh37.p13 chr 7NC_000007.13:g.7156472C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.263T=0.737
1000GenomesAmericanSub694C=0.470T=0.530
1000GenomesEast AsianSub1008C=0.671T=0.329
1000GenomesEuropeSub1006C=0.330T=0.670
1000GenomesGlobalStudy-wide5008C=0.439T=0.561
1000GenomesSouth AsianSub978C=0.530T=0.470
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.374T=0.626
The Genome Aggregation DatabaseAfricanSub8710C=0.286T=0.714
The Genome Aggregation DatabaseAmericanSub836C=0.510T=0.490
The Genome Aggregation DatabaseEast AsianSub1614C=0.668T=0.332
The Genome Aggregation DatabaseEuropeSub18476C=0.344T=0.655
The Genome Aggregation DatabaseGlobalStudy-wide29938C=0.349T=0.650
The Genome Aggregation DatabaseOtherSub302C=0.330T=0.670
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.330T=0.669
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.382T=0.618
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs69704100.000174alcohol dependence24277619

eQTL of rs6970410 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6970410 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr771389617139660E067-16812
chr771397347140635E067-15837
chr771389617139660E068-16812
chr771389617139660E069-16812
chr771397347140635E069-15837
chr771389617139660E071-16812
chr771389617139660E072-16812
chr771389617139660E073-16812
chr771397347140635E073-15837
chr771389617139660E074-16812