rs6973937

Homo sapiens
C>T
ZNF786 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0011 (333/29976,GnomAD)
T=0017 (507/29118,TOPMED)
T=0012 (62/5008,1000G)
chr7:149074254 (GRCh38.p7) (7q36.1)
AD
GWASdb2
1   publication(s)
See rs on genome
19 Enhancers around
29 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.149074254C>T
GRCh37.p13 chr 7NC_000007.13:g.148771346C>T

Gene: ZNF786, zinc finger protein 786(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ZNF786 transcriptNM_152411.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.956T=0.044
1000GenomesAmericanSub694C=0.990T=0.010
1000GenomesEast AsianSub1008C=1.000T=0.000
1000GenomesEuropeSub1006C=1.000T=0.000
1000GenomesGlobalStudy-wide5008C=0.988T=0.012
1000GenomesSouth AsianSub978C=1.000T=0.000
The Genome Aggregation DatabaseAfricanSub8722C=0.962T=0.038
The Genome Aggregation DatabaseAmericanSub838C=1.000T=0.000
The Genome Aggregation DatabaseEast AsianSub1620C=1.000T=0.000
The Genome Aggregation DatabaseEuropeSub18494C=0.999T=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29976C=0.988T=0.011
The Genome Aggregation DatabaseOtherSub302C=1.000T=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.982T=0.017
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs69739370.00037alcohol dependence20201924

eQTL of rs6973937 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6973937 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7148722984148723177E067-48169
chr7148723231148723334E067-48012
chr7148723629148723846E067-47500
chr7148726710148726842E067-44504
chr7148726962148727012E067-44334
chr7148723231148723334E068-48012
chr7148723629148723846E068-47500
chr7148726710148726842E068-44504
chr7148752304148752601E068-18745
chr7148723629148723846E069-47500
chr7148726710148726842E069-44504
chr7148752304148752601E071-18745
chr7148726710148726842E074-44504
chr7148799583148799660E08128237
chr7148799789148800080E08128443
chr7148800105148800173E08128759
chr7148800673148800808E08129327
chr7148726710148726842E082-44504
chr7148726962148727012E082-44334







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr7148723936148726679E067-44667
chr7148761954148763339E067-8007
chr7148787120148789037E06715774
chr7148723936148726679E068-44667
chr7148761954148763339E068-8007
chr7148787120148789037E06815774
chr7148723936148726679E069-44667
chr7148761954148763339E069-8007
chr7148787120148789037E06915774
chr7148723936148726679E070-44667
chr7148761954148763339E070-8007
chr7148787120148789037E07015774
chr7148723936148726679E071-44667
chr7148761954148763339E071-8007
chr7148787120148789037E07115774
chr7148723936148726679E072-44667
chr7148761954148763339E072-8007
chr7148787120148789037E07215774
chr7148723936148726679E073-44667
chr7148761954148763339E073-8007
chr7148787120148789037E07315774
chr7148723936148726679E074-44667
chr7148761954148763339E074-8007
chr7148787120148789037E07415774
chr7148723936148726679E081-44667
chr7148761954148763339E081-8007
chr7148723936148726679E082-44667
chr7148761954148763339E082-8007
chr7148787120148789037E08215774