rs6981356

Homo sapiens
T>C
LOC101929628 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0286 (8581/29928,GnomAD)
C=0283 (8258/29118,TOPMED)
C=0270 (1354/5008,1000G)
C=0333 (1283/3854,ALSPAC)
C=0342 (1269/3708,TWINSUK)
chr8:61926795 (GRCh38.p7) (8q12.3)
AD
GWASdb2
1   publication(s)
See rs on genome
7 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.61926795T>C
GRCh37.p13 chr 8NC_000008.10:g.62839354T>C

Gene: LOC101929628, uncharacterized LOC101929628(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC101929628 transcript variant X10XR_001745926.1:n.N/AIntron Variant
LOC101929628 transcript variant X11XR_001745927.1:n.N/AIntron Variant
LOC101929628 transcript variant X8XR_428354.3:n.N/AIntron Variant
LOC101929628 transcript variant X9XR_928961.2:n.N/AIntron Variant
LOC101929628 transcript variant X12XR_928962.2:n.N/AIntron Variant
LOC101929628 transcript variant X13XR_428350.3:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X14XR_428353.3:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X1XR_928953.1:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X2XR_928954.2:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X3XR_928955.1:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X4XR_928956.2:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X5XR_928957.1:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X6XR_928958.1:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X7XR_928959.1:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X15XR_928963.1:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X16XR_928965.2:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X17XR_928966.1:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X18XR_928967.1:n.N/AGenic Downstream Transcript Variant
LOC101929628 transcript variant X19XR_928968.1:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.734C=0.266
1000GenomesAmericanSub694T=0.750C=0.250
1000GenomesEast AsianSub1008T=0.936C=0.064
1000GenomesEuropeSub1006T=0.681C=0.319
1000GenomesGlobalStudy-wide5008T=0.730C=0.270
1000GenomesSouth AsianSub978T=0.550C=0.450
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.667C=0.333
The Genome Aggregation DatabaseAfricanSub8714T=0.731C=0.269
The Genome Aggregation DatabaseAmericanSub836T=0.790C=0.210
The Genome Aggregation DatabaseEast AsianSub1620T=0.923C=0.077
The Genome Aggregation DatabaseEuropeSub18456T=0.682C=0.317
The Genome Aggregation DatabaseGlobalStudy-wide29928T=0.713C=0.286
The Genome Aggregation DatabaseOtherSub302T=0.760C=0.240
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.716C=0.283
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.658C=0.342
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs69813560.000752alcohol dependence20201924

eQTL of rs6981356 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6981356 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr86284423862844292E0704884
chr86288372662884016E07044372
chr86278947962789578E081-49776
chr86278986962790044E081-49310
chr86279008262790127E081-49227
chr86279018462790444E081-48910
chr86288372662884016E08144372