rs6984462

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0178 (5350/29972,GnomAD)
T=0188 (5496/29118,TOPMED)
T=0236 (1180/5008,1000G)
T=0142 (549/3854,ALSPAC)
T=0146 (542/3708,TWINSUK)
chr8:98374366 (GRCh38.p7) (8q22.2)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.98374366C>T
GRCh37.p13 chr 8NC_000008.10:g.99386594C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.747T=0.253
1000GenomesAmericanSub694C=0.750T=0.250
1000GenomesEast AsianSub1008C=0.654T=0.346
1000GenomesEuropeSub1006C=0.856T=0.144
1000GenomesGlobalStudy-wide5008C=0.764T=0.236
1000GenomesSouth AsianSub978C=0.820T=0.180
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.858T=0.142
The Genome Aggregation DatabaseAfricanSub8730C=0.792T=0.208
The Genome Aggregation DatabaseAmericanSub836C=0.730T=0.270
The Genome Aggregation DatabaseEast AsianSub1612C=0.713T=0.287
The Genome Aggregation DatabaseEuropeSub18492C=0.849T=0.150
The Genome Aggregation DatabaseGlobalStudy-wide29972C=0.821T=0.178
The Genome Aggregation DatabaseOtherSub302C=0.780T=0.220
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.811T=0.188
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.854T=0.146
PMID Title Author Journal
22072270Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.Wang KSJ Neural Transm (Vienna)

P-Value

SNP ID p-value Traits Study
rs69844627.94E-05alcohol withdrawal symptoms22072270

eQTL of rs6984462 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6984462 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr89937444799374507E068-12087
chr89937405899374343E069-12251
chr89937444799374507E069-12087
chr89937455799374607E069-11987
chr89937405899374343E071-12251
chr89939430999395668E0717715
chr89937405899374343E073-12251
chr89942900599429130E08242411