rs6988609

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
A==0403 (11739/29118,TOPMED)
A==0373 (1866/5008,1000G)
A==0467 (1800/3854,ALSPAC)
A==0452 (1675/3708,TWINSUK)
chr8:120959818 (GRCh38.p7) (8q24.12)
AD
GWASdb2
1   publication(s)
See rs on genome
36 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.120959818A>C
GRCh37.p13 chr 8NC_000008.10:g.121972058A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.402C=0.598
1000GenomesAmericanSub694A=0.380C=0.620
1000GenomesEast AsianSub1008A=0.325C=0.675
1000GenomesEuropeSub1006A=0.456C=0.544
1000GenomesGlobalStudy-wide5008A=0.373C=0.627
1000GenomesSouth AsianSub978A=0.290C=0.710
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.467C=0.533
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.403C=0.596
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.452C=0.548
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs69886090.00064alcohol dependence20201924

eQTL of rs6988609 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6988609 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8121945002121945454E068-26604
chr8121945502121945872E068-26186
chr8121945920121946003E068-26055
chr8121946044121946162E068-25896
chr8121946193121946251E068-25807
chr8121945502121945872E069-26186
chr8121945920121946003E069-26055
chr8121972229121973105E070171
chr8121945002121945454E071-26604
chr8121945502121945872E071-26186
chr8121945920121946003E071-26055
chr8121946044121946162E071-25896
chr8121946193121946251E071-25807
chr8121945002121945454E072-26604
chr8121945502121945872E072-26186
chr8121945920121946003E072-26055
chr8121946044121946162E072-25896
chr8121946193121946251E072-25807
chr8121945002121945454E073-26604
chr8121945502121945872E073-26186
chr8121945920121946003E073-26055
chr8121945002121945454E074-26604
chr8121945502121945872E074-26186
chr8121945920121946003E074-26055
chr8121965369121965461E081-6597
chr8121965509121965563E081-6495
chr8121965682121965737E081-6321
chr8121965937121966187E081-5871
chr8121967350121967436E081-4622
chr8121967861121968080E081-3978
chr8122001050122001802E08128992
chr8122001814122002166E08129756
chr8121949997121950051E082-22007
chr8121950076121950624E082-21434
chr8121971849121972024E082-34
chr8121972229121973105E082171