rs7016174

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0183 (5485/29974,GnomAD)
C=0227 (6617/29118,TOPMED)
C=0235 (1177/5008,1000G)
C=0060 (232/3854,ALSPAC)
C=0047 (175/3708,TWINSUK)
chr8:100799020 (GRCh38.p7) (8q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
21 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.100799020A>C
GRCh37.p13 chr 8NC_000008.10:g.101811248A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.538C=0.462
1000GenomesAmericanSub694A=0.780C=0.220
1000GenomesEast AsianSub1008A=0.711C=0.289
1000GenomesEuropeSub1006A=0.947C=0.053
1000GenomesGlobalStudy-wide5008A=0.765C=0.235
1000GenomesSouth AsianSub978A=0.930C=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.940C=0.060
The Genome Aggregation DatabaseAfricanSub8714A=0.575C=0.425
The Genome Aggregation DatabaseAmericanSub838A=0.790C=0.210
The Genome Aggregation DatabaseEast AsianSub1616A=0.686C=0.314
The Genome Aggregation DatabaseEuropeSub18504A=0.941C=0.058
The Genome Aggregation DatabaseGlobalStudy-wide29974A=0.817C=0.183
The Genome Aggregation DatabaseOtherSub302A=0.940C=0.060
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.772C=0.227
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.953C=0.047
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs70161740.0001alcohol consumption23743675

eQTL of rs7016174 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7016174 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8101773554101775046E068-36202
chr8101847470101848214E06836222
chr8101762717101763214E071-48034
chr8101764400101764498E071-46750
chr8101764560101764751E071-46497
chr8101764770101764823E071-46425
chr8101803597101803661E072-7587
chr8101803758101804338E074-6910
chr8101804391101804510E074-6738
chr8101847470101848214E07436222
chr8101848259101848339E07437011
chr8101859230101859295E07447982
chr8101775773101775823E081-35425
chr8101775832101775882E081-35366
chr8101775951101776079E081-35169
chr8101803597101803661E081-7587
chr8101803758101804338E081-6910
chr8101804391101804510E081-6738
chr8101851627101851825E08140379
chr8101851845101851917E08140597
chr8101775334101775644E082-35604