rs7016436

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0127 (3819/29950,GnomAD)
A=0140 (4097/29118,TOPMED)
A=0175 (876/5008,1000G)
A=0059 (227/3854,ALSPAC)
A=0047 (174/3708,TWINSUK)
chr8:100798996 (GRCh38.p7) (8q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
21 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.100798996G>A
GRCh37.p13 chr 8NC_000008.10:g.101811224G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.756A=0.244
1000GenomesAmericanSub694G=0.800A=0.200
1000GenomesEast AsianSub1008G=0.711A=0.289
1000GenomesEuropeSub1006G=0.948A=0.052
1000GenomesGlobalStudy-wide5008G=0.825A=0.175
1000GenomesSouth AsianSub978G=0.930A=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.941A=0.059
The Genome Aggregation DatabaseAfricanSub8712G=0.762A=0.238
The Genome Aggregation DatabaseAmericanSub836G=0.800A=0.200
The Genome Aggregation DatabaseEast AsianSub1606G=0.688A=0.312
The Genome Aggregation DatabaseEuropeSub18494G=0.942A=0.057
The Genome Aggregation DatabaseGlobalStudy-wide29950G=0.872A=0.127
The Genome Aggregation DatabaseOtherSub302G=0.950A=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.859A=0.140
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.953A=0.047
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs70164364.21E-05alcohol consumption23743675

eQTL of rs7016436 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7016436 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8101773554101775046E068-36178
chr8101847470101848214E06836246
chr8101762717101763214E071-48010
chr8101764400101764498E071-46726
chr8101764560101764751E071-46473
chr8101764770101764823E071-46401
chr8101803597101803661E072-7563
chr8101803758101804338E074-6886
chr8101804391101804510E074-6714
chr8101847470101848214E07436246
chr8101848259101848339E07437035
chr8101859230101859295E07448006
chr8101775773101775823E081-35401
chr8101775832101775882E081-35342
chr8101775951101776079E081-35145
chr8101803597101803661E081-7563
chr8101803758101804338E081-6886
chr8101804391101804510E081-6714
chr8101851627101851825E08140403
chr8101851845101851917E08140621
chr8101775334101775644E082-35580