SNP Detail Info-rs7034275

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 9	NC_000009.12:g.7067344G>C
GRCh37.p13 chr 9	NC_000009.11:g.7067344G>C

Gene: KDM4C, lysine demethylase 4C(plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
KDM4C transcript variant 3	NM_001146695.1:c.	N/A	Intron Variant
KDM4C transcript variant 4	NM_001146696.1:c.	N/A	Intron Variant
KDM4C transcript variant 5	NM_001304339.1:c.	N/A	Intron Variant
KDM4C transcript variant 6	NM_001304340.1:c.	N/A	Intron Variant
KDM4C transcript variant 1	NM_015061.3:c.	N/A	Intron Variant
KDM4C transcript variant 7	NM_001304341.1:c.	N/A	Genic Downstream Transcript Variant
KDM4C transcript variant 8	NR_130707.1:n.	N/A	Genic Downstream Transcript Variant
KDM4C transcript variant X1	XM_006716741.2:c.	N/A	Intron Variant
KDM4C transcript variant X4	XM_011517811.2:c.	N/A	Intron Variant
KDM4C transcript variant X6	XM_011517812.2:c.	N/A	Intron Variant
KDM4C transcript variant X14	XM_011517816.2:c.	N/A	Intron Variant
KDM4C transcript variant X2	XM_017014498.1:c.	N/A	Intron Variant
KDM4C transcript variant X3	XM_017014499.1:c.	N/A	Intron Variant
KDM4C transcript variant X5	XM_017014500.1:c.	N/A	Intron Variant
KDM4C transcript variant X7	XM_017014501.1:c.	N/A	Intron Variant
KDM4C transcript variant X13	XM_017014503.1:c.	N/A	Intron Variant
KDM4C transcript variant X16	XM_017014505.1:c.	N/A	Intron Variant
KDM4C transcript variant X17	XM_017014506.1:c.	N/A	Intron Variant
KDM4C transcript variant X9	XM_017014502.1:c.	N/A	Genic Downstream Transcript Variant
KDM4C transcript variant X15	XM_017014504.1:c.	N/A	Genic Downstream Transcript Variant
KDM4C transcript variant X8	XR_001746252.1:n.	N/A	Intron Variant
KDM4C transcript variant X10	XR_001746253.1:n.	N/A	Intron Variant
KDM4C transcript variant X11	XR_001746254.1:n.	N/A	Intron Variant
KDM4C transcript variant X12	XR_001746255.1:n.	N/A	Intron Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.722	C=0.278
1000Genomes	American	Sub	694	G=0.680	C=0.320
1000Genomes	East Asian	Sub	1008	G=0.810	C=0.190
1000Genomes	Europe	Sub	1006	G=0.544	C=0.456
1000Genomes	Global	Study-wide	5008	G=0.714	C=0.286
1000Genomes	South Asian	Sub	978	G=0.800	C=0.200
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.540	C=0.460
The Genome Aggregation Database	African	Sub	8708	G=0.703	C=0.297
The Genome Aggregation Database	American	Sub	838	G=0.710	C=0.290
The Genome Aggregation Database	East Asian	Sub	1622	G=0.819	C=0.181
The Genome Aggregation Database	Europe	Sub	18462	G=0.509	C=0.491
The Genome Aggregation Database	Global	Study-wide	29932	G=0.589	C=0.410
The Genome Aggregation Database	Other	Sub	302	G=0.660	C=0.340
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.641	C=0.358
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.551	C=0.449

PMID	Title	Author	Journal
19268276	Genome-wide association study of smoking initiation and current smoking.	Vink JM	Am J Hum Genet

P-Value

SNP ID	p-value	Traits	Study
rs7034275	0.000381	nicotine smoking	19268276

eQTL of rs7034275 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs7034275 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Enhancer Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr9	7052503	7053138	E068	-14206
chr9	7056766	7057012	E068	-10332
chr9	7057223	7057335	E068	-10009
chr9	7057342	7057422	E068	-9922
chr9	7057457	7058000	E068	-9344
chr9	7058090	7058230	E068	-9114
chr9	7058310	7058379	E068	-8965
chr9	7058388	7058453	E068	-8891
chr9	7058500	7058568	E068	-8776
chr9	7085202	7085252	E068	17858
chr9	7085361	7085412	E068	18017
chr9	7052503	7053138	E069	-14206
chr9	7053246	7053364	E069	-13980
chr9	7053377	7053446	E069	-13898
chr9	7053484	7053547	E069	-13797
chr9	7057457	7058000	E069	-9344
chr9	7058090	7058230	E069	-9114
chr9	7078796	7079177	E069	11452
chr9	7082561	7082720	E069	15217
chr9	7085202	7085252	E069	17858
chr9	7085361	7085412	E069	18017
chr9	7088153	7088231	E069	20809
chr9	7088301	7088405	E069	20957
chr9	7037273	7037323	E070	-30021
chr9	7084789	7084843	E071	17445
chr9	7085202	7085252	E071	17858
chr9	7085361	7085412	E071	18017
chr9	7082561	7082720	E072	15217
chr9	7052503	7053138	E073	-14206
chr9	7053246	7053364	E073	-13980
chr9	7053377	7053446	E073	-13898
chr9	7056387	7056589	E074	-10755
chr9	7056766	7057012	E074	-10332
chr9	7057457	7058000	E074	-9344
chr9	7078796	7079177	E074	11452
chr9	7084789	7084843	E074	17445
chr9	7085202	7085252	E074	17858
chr9	7085361	7085412	E074	18017
chr9	7115746	7115884	E074	48402
chr9	7052503	7053138	E081	-14206
chr9	7053246	7053364	E081	-13980
chr9	7053377	7053446	E081	-13898
chr9	7053246	7053364	E082	-13980
chr9	7053377	7053446	E082	-13898
chr9	7055053	7055161	E082	-12183
chr9	7088501	7089004	E082	21157
chr9	7089202	7089715	E082	21858

rs7034275

Genomic Coordinates

Gene: KDM4C, lysine demethylase 4C(plus strand)

Population Frequency

P-Value

eQTL of rs7034275 in Brain tissues (GTEx Analysis Release V7)

meQTL of rs7034275 in Fetal Brain

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)