rs7035064

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0069 (2073/29970,GnomAD)
G=0067 (1965/29118,TOPMED)
G=0045 (223/5008,1000G)
G=0089 (344/3854,ALSPAC)
G=0082 (305/3708,TWINSUK)

Position: chr9:99169458 (GRCh38.p7) (9q22.33)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 70 Enhancers around

Promoter: 0 Promoter around

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 9	NC_000009.12:g.99169458A>G
GRCh37.p13 chr 9	NC_000009.11:g.101931740A>G

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.946	G=0.054
1000Genomes	American	Sub	694	A=0.950	G=0.050
1000Genomes	East Asian	Sub	1008	A=1.000	G=0.000
1000Genomes	Europe	Sub	1006	A=0.919	G=0.081
1000Genomes	Global	Study-wide	5008	A=0.955	G=0.045
1000Genomes	South Asian	Sub	978	A=0.960	G=0.040
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.911	G=0.089
The Genome Aggregation Database	African	Sub	8728	A=0.946	G=0.054
The Genome Aggregation Database	American	Sub	838	A=0.970	G=0.030
The Genome Aggregation Database	East Asian	Sub	1620	A=1.000	G=0.000
The Genome Aggregation Database	Europe	Sub	18482	A=0.916	G=0.083
The Genome Aggregation Database	Global	Study-wide	29970	A=0.930	G=0.069
The Genome Aggregation Database	Other	Sub	302	A=0.920	G=0.080
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.932	G=0.067
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.918	G=0.082

PMID	Title	Author	Journal
22488850	Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.	Zuo L	Am J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID	p-value	Traits	Study
rs7035064	6.8E-06	alcohol and nictotine co-dependence	22488850

eQTL of rs7035064 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs7035064 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr9	101897138	101897651	E067	-34089
chr9	101897708	101898121	E067	-33619
chr9	101936100	101936617	E067	4360
chr9	101936847	101936983	E067	5107
chr9	101936100	101936617	E068	4360
chr9	101936847	101936983	E068	5107
chr9	101980415	101980465	E068	48675
chr9	101897708	101898121	E069	-33619
chr9	101932304	101932763	E069	564
chr9	101932778	101932970	E069	1038
chr9	101932983	101933079	E069	1243
chr9	101936100	101936617	E069	4360
chr9	101932304	101932763	E070	564
chr9	101932778	101932970	E070	1038
chr9	101932983	101933079	E070	1243
chr9	101933081	101933121	E070	1341
chr9	101963684	101963738	E070	31944
chr9	101964417	101964467	E070	32677
chr9	101980742	101980810	E070	49002
chr9	101980821	101980871	E070	49081
chr9	101981099	101981212	E070	49359
chr9	101892306	101892817	E071	-38923
chr9	101892971	101893265	E071	-38475
chr9	101897708	101898121	E071	-33619
chr9	101932304	101932763	E071	564
chr9	101932778	101932970	E071	1038
chr9	101936100	101936617	E071	4360
chr9	101936847	101936983	E071	5107
chr9	101932778	101932970	E072	1038
chr9	101932983	101933079	E072	1243
chr9	101933081	101933121	E072	1341
chr9	101936100	101936617	E072	4360
chr9	101936847	101936983	E072	5107
chr9	101946356	101947740	E073	14616
chr9	101890976	101891056	E074	-40684
chr9	101897138	101897651	E074	-34089
chr9	101897708	101898121	E074	-33619
chr9	101936100	101936617	E074	4360
chr9	101936847	101936983	E074	5107
chr9	101886060	101886169	E081	-45571
chr9	101886352	101886662	E081	-45078
chr9	101886918	101887017	E081	-44723
chr9	101887196	101887647	E081	-44093
chr9	101887690	101888271	E081	-43469
chr9	101888316	101888404	E081	-43336
chr9	101888550	101888913	E081	-42827
chr9	101889464	101889613	E081	-42127
chr9	101889710	101890302	E081	-41438
chr9	101890359	101890598	E081	-41142
chr9	101897138	101897651	E081	-34089
chr9	101897708	101898121	E081	-33619
chr9	101932778	101932970	E081	1038
chr9	101946356	101947740	E081	14616
chr9	101887196	101887647	E082	-44093
chr9	101887690	101888271	E082	-43469
chr9	101888316	101888404	E082	-43336
chr9	101888550	101888913	E082	-42827
chr9	101889165	101889375	E082	-42365
chr9	101889464	101889613	E082	-42127
chr9	101889710	101890302	E082	-41438
chr9	101890359	101890598	E082	-41142
chr9	101890976	101891056	E082	-40684
chr9	101891188	101891777	E082	-39963
chr9	101897138	101897651	E082	-34089
chr9	101897708	101898121	E082	-33619
chr9	101932304	101932763	E082	564
chr9	101932778	101932970	E082	1038
chr9	101932983	101933079	E082	1243
chr9	101933081	101933121	E082	1341
chr9	101948106	101948489	E082	16366