rs7035993

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0303 (9092/29938,GnomAD)
G=0366 (10669/29118,TOPMED)
G=0359 (1800/5008,1000G)
G=0164 (633/3854,ALSPAC)
G=0167 (620/3708,TWINSUK)
chr9:786996 (GRCh38.p7) (9p24.3)
ND
GWASdb2
1   publication(s)
See rs on genome
134 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.786996A>G
GRCh37.p13 chr 9NC_000009.11:g.786996A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.291G=0.709
1000GenomesAmericanSub694A=0.650G=0.350
1000GenomesEast AsianSub1008A=0.814G=0.186
1000GenomesEuropeSub1006A=0.824G=0.176
1000GenomesGlobalStudy-wide5008A=0.641G=0.359
1000GenomesSouth AsianSub978A=0.740G=0.260
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.836G=0.164
The Genome Aggregation DatabaseAfricanSub8700A=0.384G=0.616
The Genome Aggregation DatabaseAmericanSub838A=0.650G=0.350
The Genome Aggregation DatabaseEast AsianSub1610A=0.800G=0.200
The Genome Aggregation DatabaseEuropeSub18488A=0.835G=0.165
The Genome Aggregation DatabaseGlobalStudy-wide29938A=0.696G=0.303
The Genome Aggregation DatabaseOtherSub302A=0.790G=0.210
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.633G=0.366
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.833G=0.167
PMID Title Author Journal
22377092ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies.Wang KSDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs70359934.37E-05nicotine dependence (smoking)22377092

eQTL of rs7035993 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7035993 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr9737355737447E067-49549
chr9737468739037E067-47959
chr9744333744478E067-42518
chr9744539744655E067-42341
chr9744718745339E067-41657
chr9749552750213E067-36783
chr9750326750572E067-36424
chr9760909761098E067-25898
chr9761106761197E067-25799
chr9761200761269E067-25727
chr9761318761387E067-25609
chr9761467761805E067-25191
chr9761903761995E067-25001
chr9762173762233E067-24763
chr9763945764456E067-22540
chr9737468739037E068-47959
chr9743767743825E068-43171
chr9744008744095E068-42901
chr9744231744311E068-42685
chr9744333744478E068-42518
chr9744539744655E068-42341
chr9744718745339E068-41657
chr9745340745769E068-41227
chr9745900746063E068-40933
chr9746131746369E068-40627
chr9750326750572E068-36424
chr9750659750965E068-36031
chr9751024752594E068-34402
chr9761467761805E068-25191
chr9761903761995E068-25001
chr9737355737447E069-49549
chr9737468739037E069-47959
chr9743003743104E069-43892
chr9743318743436E069-43560
chr9743767743825E069-43171
chr9744008744095E069-42901
chr9744231744311E069-42685
chr9744333744478E069-42518
chr9744539744655E069-42341
chr9744718745339E069-41657
chr9745340745769E069-41227
chr9745900746063E069-40933
chr9746131746369E069-40627
chr9749552750213E069-36783
chr9754238754485E069-32511
chr9754487754540E069-32456
chr9754565754959E069-32037
chr9755646756439E069-30557
chr9760909761098E069-25898
chr9761106761197E069-25799
chr9761200761269E069-25727
chr9761318761387E069-25609
chr9761467761805E069-25191
chr9761903761995E069-25001
chr9737468739037E071-47959
chr9743003743104E071-43892
chr9743318743436E071-43560
chr9743767743825E071-43171
chr9744008744095E071-42901
chr9744231744311E071-42685
chr9744333744478E071-42518
chr9744539744655E071-42341
chr9744718745339E071-41657
chr9745340745769E071-41227
chr9745900746063E071-40933
chr9746131746369E071-40627
chr9748880749492E071-37504
chr9749552750213E071-36783
chr9750326750572E071-36424
chr9750659750965E071-36031
chr9751024752594E071-34402
chr9760461760627E071-26369
chr9760909761098E071-25898
chr9761106761197E071-25799
chr9761200761269E071-25727
chr9761318761387E071-25609
chr9761467761805E071-25191
chr9737355737447E072-49549
chr9737468739037E072-47959
chr9744333744478E072-42518
chr9744539744655E072-42341
chr9744718745339E072-41657
chr9745340745769E072-41227
chr9750326750572E072-36424
chr9760332760409E072-26587
chr9760461760627E072-26369
chr9760909761098E072-25898
chr9761106761197E072-25799
chr9761200761269E072-25727
chr9761318761387E072-25609
chr9761467761805E072-25191
chr9761903761995E072-25001
chr9762173762233E072-24763
chr9737468739037E073-47959
chr9743767743825E073-43171
chr9744008744095E073-42901
chr9744231744311E073-42685
chr9744333744478E073-42518
chr9744539744655E073-42341
chr9744718745339E073-41657
chr9745340745769E073-41227
chr9745900746063E073-40933
chr9746131746369E073-40627
chr9751024752594E073-34402
chr9760909761098E073-25898
chr9761106761197E073-25799
chr9761200761269E073-25727
chr9761318761387E073-25609
chr9737355737447E074-49549
chr9737468739037E074-47959
chr9739155739257E074-47739
chr9743003743104E074-43892
chr9743318743436E074-43560
chr9743767743825E074-43171
chr9744008744095E074-42901
chr9744231744311E074-42685
chr9744333744478E074-42518
chr9744539744655E074-42341
chr9744718745339E074-41657
chr9745340745769E074-41227
chr9745900746063E074-40933
chr9746131746369E074-40627
chr9750659750965E074-36031
chr9751024752594E074-34402
chr9760909761098E074-25898
chr9761106761197E074-25799
chr9761200761269E074-25727
chr9761318761387E074-25609
chr9761467761805E074-25191
chr9761903761995E074-25001
chr9762173762233E074-24763
chr9750326750572E081-36424
chr9750326750572E082-36424
chr9750659750965E082-36031