rs7042018

Homo sapiens
A>G
RBM18 : Non Coding Transcript Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0104 (3146/29990,GnomAD)
A==0155 (4517/29118,TOPMED)
A==0103 (515/5008,1000G)
A==0041 (158/3854,ALSPAC)
A==0037 (139/3708,TWINSUK)
chr9:122241249 (GRCh38.p7) (9q33.2)
AD
GWASdb2
1   publication(s)
See rs on genome
129 Enhancers around
25 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.122241249A>G
GRCh37.p13 chr 9NC_000009.11:g.125003528A>G

Gene: RBM18, RNA binding motif protein 18(minus strand)

Molecule type Change Amino acid[Codon] SO Term
RBM18 transcript variant 1NM_033117.3:c.N/A3 Prime UTR Variant
RBM18 transcript variant 2NR_027125.1:n.149...NR_027125.1:n.1499T>CT>CNon Coding Transcript Variant
RBM18 transcript variant 3NR_027126.1:n.146...NR_027126.1:n.1468T>CT>CNon Coding Transcript Variant
RBM18 transcript variant X1XM_006717319.1:c.N/A3 Prime UTR Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.333G=0.667
1000GenomesAmericanSub694A=0.050G=0.950
1000GenomesEast AsianSub1008A=0.000G=1.000
1000GenomesEuropeSub1006A=0.034G=0.966
1000GenomesGlobalStudy-wide5008A=0.103G=0.897
1000GenomesSouth AsianSub978A=0.010G=0.990
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.041G=0.959
The Genome Aggregation DatabaseAfricanSub8722A=0.288G=0.712
The Genome Aggregation DatabaseAmericanSub838A=0.050G=0.950
The Genome Aggregation DatabaseEast AsianSub1620A=0.001G=0.999
The Genome Aggregation DatabaseEuropeSub18508A=0.031G=0.968
The Genome Aggregation DatabaseGlobalStudy-wide29990A=0.104G=0.895
The Genome Aggregation DatabaseOtherSub302A=0.040G=0.960
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.155G=0.844
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.037G=0.963
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs70420180.00047alcohol dependence20201924

eQTL of rs7042018 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7042018 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr9124953586124953687E067-49841
chr9125002045125002095E067-1433
chr9125013680125014053E06710152
chr9125014253125014313E06710725
chr9125014489125014539E06710961
chr9125015079125015407E06711551
chr9125015415125015546E06711887
chr9125016522125016664E06712994
chr9125016682125016832E06713154
chr9125017015125017231E06713487
chr9125023692125023805E06720164
chr9125023860125024185E06720332
chr9125024382125024422E06720854
chr9125024501125024633E06720973
chr9125024682125024769E06721154
chr9125024779125024831E06721251
chr9125025367125025503E06721839
chr9125025551125025672E06722023
chr9125014253125014313E06810725
chr9125014489125014539E06810961
chr9125015079125015407E06811551
chr9125015415125015546E06811887
chr9125017015125017231E06813487
chr9125028756125028869E06825228
chr9125013680125014053E06910152
chr9125014253125014313E06910725
chr9125014489125014539E06910961
chr9125015079125015407E06911551
chr9125015415125015546E06911887
chr9125017015125017231E06913487
chr9125023692125023805E06920164
chr9125023860125024185E06920332
chr9125025367125025503E06921839
chr9125025551125025672E06922023
chr9124953586124953687E070-49841
chr9124953770124954062E070-49466
chr9124959798124960446E070-43082
chr9124960744124960802E070-42726
chr9124960829124960919E070-42609
chr9124961021124961086E070-42442
chr9124966136124966219E070-37309
chr9124966654124966843E070-36685
chr9124966969124967045E070-36483
chr9124967166124967344E070-36184
chr9124967583124967640E070-35888
chr9124967690124967740E070-35788
chr9124968070124968155E070-35373
chr9124968404124968480E070-35048
chr9124968537124968812E070-34716
chr9124968837124968984E070-34544
chr9124968985124969099E070-34429
chr9124971444124971502E070-32026
chr9124971630124971692E070-31836
chr9124971717124971777E070-31751
chr9124977664124977889E070-25639
chr9125024382125024422E07020854
chr9125024501125024633E07020973
chr9125024682125024769E07021154
chr9125024779125024831E07021251
chr9125025367125025503E07021839
chr9125025551125025672E07022023
chr9124985185124985573E071-17955
chr9124985740124985801E071-17727
chr9124985898124985948E071-17580
chr9124985955124986005E071-17523
chr9125013680125014053E07110152
chr9125014489125014539E07110961
chr9125015079125015407E07111551
chr9125015415125015546E07111887
chr9125016522125016664E07112994
chr9125016682125016832E07113154
chr9125017015125017231E07113487
chr9125017579125017629E07114051
chr9125017755125017805E07114227
chr9125017900125017950E07114372
chr9125025367125025503E07121839
chr9125025551125025672E07122023
chr9125010780125010922E0727252
chr9125010949125011313E0727421
chr9125013680125014053E07210152
chr9125014253125014313E07210725
chr9125014489125014539E07210961
chr9125015079125015407E07211551
chr9125015415125015546E07211887
chr9125017015125017231E07213487
chr9125017755125017805E07214227
chr9125017900125017950E07214372
chr9125023860125024185E07220332
chr9125024382125024422E07220854
chr9125024501125024633E07220973
chr9125024682125024769E07221154
chr9125024779125024831E07221251
chr9125025367125025503E07221839
chr9125025551125025672E07222023
chr9125013680125014053E07310152
chr9125014253125014313E07310725
chr9125014489125014539E07310961
chr9125015079125015407E07311551
chr9125015415125015546E07311887
chr9125023400125023460E07319872
chr9125023562125023662E07320034
chr9125023692125023805E07320164
chr9125023860125024185E07320332
chr9125024382125024422E07320854
chr9125024501125024633E07320973
chr9125024682125024769E07321154
chr9125024779125024831E07321251
chr9125025367125025503E07321839
chr9125025551125025672E07322023
chr9125028756125028869E07325228
chr9124985898124985948E074-17580
chr9124985955124986005E074-17523
chr9125013680125014053E07410152
chr9125014253125014313E07410725
chr9125014489125014539E07410961
chr9125015079125015407E07411551
chr9125015415125015546E07411887
chr9125016682125016832E07413154
chr9125017015125017231E07413487
chr9125025367125025503E07421839
chr9125025551125025672E07422023
chr9124966654124966843E081-36685
chr9124966969124967045E081-36483
chr9124970409124970494E081-33034
chr9124970555124970613E081-32915
chr9125024779125024831E08121251
chr9125025367125025503E08121839
chr9125025551125025672E08122023
chr9125024501125024633E08220973










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr9124990342124991948E067-11580
chr9125026240125028264E06722712
chr9124990342124991948E068-11580
chr9125026240125028264E06822712
chr9124975422124977054E069-26474
chr9124990342124991948E069-11580
chr9125026240125028264E06922712
chr9124974793124974944E070-28584
chr9124975030124975116E070-28412
chr9124975422124977054E070-26474
chr9124986358124986408E070-17120
chr9124990342124991948E070-11580
chr9125026240125028264E07022712
chr9124990342124991948E071-11580
chr9125026240125028264E07122712
chr9124990342124991948E072-11580
chr9125026240125028264E07222712
chr9125026240125028264E07322712
chr9124990342124991948E074-11580
chr9125026240125028264E07422712
chr9124975030124975116E082-28412
chr9124975422124977054E082-26474
chr9124986358124986408E082-17120
chr9124990342124991948E082-11580
chr9125026240125028264E08222712