rs705326

Homo sapiens
T>A / T>C / T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T==0463 (13870/29908,GnomAD)
T==0491 (14319/29118,TOPMED)
T==0390 (1952/5008,1000G)
C=0484 (1864/3854,ALSPAC)
C=0476 (1764/3708,TWINSUK)
chr7:98562879 (GRCh38.p7) (7q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.98562879T>A
GRCh38.p7 chr 7NC_000007.14:g.98562879T>C
GRCh38.p7 chr 7NC_000007.14:g.98562879T>G
GRCh37.p13 chr 7NC_000007.13:g.98192191T>A
GRCh37.p13 chr 7NC_000007.13:g.98192191T>C
GRCh37.p13 chr 7NC_000007.13:g.98192191T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.476C=0.524
1000GenomesAmericanSub694T=0.350C=0.650
1000GenomesEast AsianSub1008T=0.171C=0.829
1000GenomesEuropeSub1006T=0.506C=0.494
1000GenomesGlobalStudy-wide5008T=0.390C=0.610
1000GenomesSouth AsianSub978T=0.410C=0.590
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.516C=0.484
The Genome Aggregation DatabaseAfricanSub8698T=0.471C=0.529
The Genome Aggregation DatabaseAmericanSub838T=0.350C=0.650
The Genome Aggregation DatabaseEast AsianSub1612T=0.201C=0.799
The Genome Aggregation DatabaseEuropeSub18458T=0.489C=0.510
The Genome Aggregation DatabaseGlobalStudy-wide29908T=0.463C=0.536
The Genome Aggregation DatabaseOtherSub302T=0.420C=0.580
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.491C=0.508
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.524C=0.476
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs7053260.000812alcohol dependence21314694

eQTL of rs705326 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs705326 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr786232198623269E07032346
chr786011098601377E08110236