rs705362

Homo sapiens
A>G
CDK14 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0044 (1334/29980,GnomAD)
A==0056 (1635/29118,TOPMED)
A==0056 (278/5008,1000G)
A==0056 (216/3854,ALSPAC)
A==0058 (214/3708,TWINSUK)
chr7:91153219 (GRCh38.p7) (7q21.13)
AD
GWASdb2
1   publication(s)
See rs on genome
69 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.91153219A>G
GRCh37.p13 chr 7NC_000007.13:g.90782534A>G

Gene: CDK14, cyclin-dependent kinase 14(plus strand)

Molecule type Change Amino acid[Codon] SO Term
CDK14 transcript variant 1NM_001287135.1:c.N/AIntron Variant
CDK14 transcript variant 3NM_001287136.1:c.N/AIntron Variant
CDK14 transcript variant 4NM_001287137.1:c.N/AIntron Variant
CDK14 transcript variant 2NM_012395.3:c.N/AIntron Variant
CDK14 transcript variant X2XM_005250436.3:c.N/AIntron Variant
CDK14 transcript variant X5XM_005250438.3:c.N/AIntron Variant
CDK14 transcript variant X4XM_005250439.2:c.N/AIntron Variant
CDK14 transcript variant X3XM_017012320.1:c.N/AIntron Variant
CDK14 transcript variant X6XM_017012321.1:c.N/AIntron Variant
CDK14 transcript variant X1XM_011516306.2:c.N/AGenic Downstream Transcript Variant
CDK14 transcript variant X8XM_011516307.2:c.N/AGenic Downstream Transcript Variant
CDK14 transcript variant X7XM_017012322.1:c.N/AGenic Downstream Transcript Variant
CDK14 transcript variant X9XR_927477.2:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.036G=0.964
1000GenomesAmericanSub694A=0.050G=0.950
1000GenomesEast AsianSub1008A=0.014G=0.986
1000GenomesEuropeSub1006A=0.065G=0.935
1000GenomesGlobalStudy-wide5008A=0.056G=0.944
1000GenomesSouth AsianSub978A=0.120G=0.880
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.056G=0.944
The Genome Aggregation DatabaseAfricanSub8730A=0.037G=0.963
The Genome Aggregation DatabaseAmericanSub836A=0.030G=0.970
The Genome Aggregation DatabaseEast AsianSub1616A=0.006G=0.994
The Genome Aggregation DatabaseEuropeSub18496A=0.050G=0.949
The Genome Aggregation DatabaseGlobalStudy-wide29980A=0.044G=0.955
The Genome Aggregation DatabaseOtherSub302A=0.110G=0.890
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.056G=0.943
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.058G=0.942
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs7053620.000534alcohol dependence21314694

eQTL of rs705362 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs705362 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr79076656890766696E068-15838
chr79082123490821304E06838700
chr79082132190821567E06838787
chr79074920190749285E070-33249
chr79074939490749586E070-32948
chr79075553890755614E070-26920
chr79075575190755896E070-26638
chr79075593890756883E070-25651
chr79076459790764690E070-17844
chr79076472790764985E070-17549
chr79076499890765370E070-17164
chr79079814590798401E07015611
chr79079841990798760E07015885
chr79079876790799149E07016233
chr79079920490799425E07016670
chr79082391590824136E07041381
chr79082416890824508E07041634
chr79082847090829954E07045936
chr79083051390830719E07047979
chr79083074690831431E07048212
chr79083150190831551E07048967
chr79074177390742895E081-39639
chr79075553890755614E081-26920
chr79075575190755896E081-26638
chr79075593890756883E081-25651
chr79076459790764690E081-17844
chr79076472790764985E081-17549
chr79076656890766696E081-15838
chr79076690290766991E081-15543
chr79076704690767111E081-15423
chr79076716590767351E081-15183
chr79077725890777318E081-5216
chr79077794590777995E081-4539
chr79077813790778197E081-4337
chr79077852090779456E081-3078
chr79077955590779609E081-2925
chr79078050090780560E081-1974
chr79078400390784053E0811469
chr79078415990784313E0811625
chr79078448390784574E0811949
chr79078481290784991E0812278
chr79078513990785251E0812605
chr79078537090785513E0812836
chr79078653390786705E0813999
chr79079841990798760E08115885
chr79079876790799149E08116233
chr79079920490799425E08116670
chr79082221490822306E08139680
chr79082236090822424E08139826
chr79082263390822792E08140099
chr79082284490822964E08140310
chr79082391590824136E08141381
chr79082847090829954E08145936
chr79083051390830719E08147979
chr79083074690831431E08148212
chr79074177390742895E082-39639
chr79075593890756883E082-25651
chr79077461390774757E082-7777
chr79077813790778197E082-4337
chr79077852090779456E082-3078
chr79077955590779609E082-2925
chr79078513990785251E0822605
chr79078537090785513E0822836
chr79078653390786705E0823999
chr79082221490822306E08239680
chr79082847090829954E08245936
chr79083051390830719E08247979
chr79083074690831431E08248212
chr79083150190831551E08248967