rs7068193

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0419 (12546/29896,GnomAD)
A=0452 (13176/29118,TOPMED)
A=0496 (2484/5008,1000G)
A=0345 (1328/3854,ALSPAC)
A=0331 (1226/3708,TWINSUK)
chr10:84035862 (GRCh38.p7) (10q23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
2 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.84035862G>A
GRCh37.p13 chr 10NC_000010.10:g.85795618G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.380A=0.620
1000GenomesAmericanSub694G=0.540A=0.460
1000GenomesEast AsianSub1008G=0.501A=0.499
1000GenomesEuropeSub1006G=0.669A=0.331
1000GenomesGlobalStudy-wide5008G=0.504A=0.496
1000GenomesSouth AsianSub978G=0.480A=0.520
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.655A=0.345
The Genome Aggregation DatabaseAfricanSub8698G=0.426A=0.574
The Genome Aggregation DatabaseAmericanSub838G=0.560A=0.440
The Genome Aggregation DatabaseEast AsianSub1610G=0.557A=0.443
The Genome Aggregation DatabaseEuropeSub18448G=0.658A=0.341
The Genome Aggregation DatabaseGlobalStudy-wide29896G=0.580A=0.419
The Genome Aggregation DatabaseOtherSub302G=0.450A=0.550
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.547A=0.452
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.669A=0.331
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs70681930.000064alcoholismpha002893
rs70681930.000064alcohol dependence(Early Onset)20201924
rs70681930.00011alcohol dependence20201924

eQTL of rs7068193 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7068193 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr108575954585759629E070-35989
chr108575974285759810E070-35808
chr108576019985760257E070-35361

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr108580917085809315E06813552
chr108580917085809315E07113552