rs7069564

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0158 (4739/29946,GnomAD)
T=0164 (4778/29118,TOPMED)
T=0232 (1163/5008,1000G)
T=0148 (572/3854,ALSPAC)
T=0166 (616/3708,TWINSUK)
chr10:111137312 (GRCh38.p7) (10q25.2)
CD
GWASdb2
1   publication(s)
See rs on genome
22 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.111137312C>T
GRCh37.p13 chr 10NC_000010.10:g.112897070C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.874T=0.126
1000GenomesAmericanSub694C=0.740T=0.260
1000GenomesEast AsianSub1008C=0.625T=0.375
1000GenomesEuropeSub1006C=0.854T=0.146
1000GenomesGlobalStudy-wide5008C=0.768T=0.232
1000GenomesSouth AsianSub978C=0.700T=0.300
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.852T=0.148
The Genome Aggregation DatabaseAfricanSub8726C=0.853T=0.147
The Genome Aggregation DatabaseAmericanSub836C=0.720T=0.280
The Genome Aggregation DatabaseEast AsianSub1616C=0.616T=0.384
The Genome Aggregation DatabaseEuropeSub18466C=0.862T=0.137
The Genome Aggregation DatabaseGlobalStudy-wide29946C=0.841T=0.158
The Genome Aggregation DatabaseOtherSub302C=0.810T=0.190
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.835T=0.164
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.834T=0.166
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs70695640.0000788cocaine dependence23958962
rs70695640.000248cocaine dependence23958962

eQTL of rs7069564 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7069564 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10112888183112888477E067-8593
chr10112888603112888882E067-8188
chr10112889028112889082E067-7988
chr10112889248112889764E067-7306
chr10112889789112889889E067-7181
chr10112889028112889082E068-7988
chr10112873507112873640E069-23430
chr10112888603112888882E069-8188
chr10112889028112889082E069-7988
chr10112889248112889764E069-7306
chr10112905736112906481E0698666
chr10112889028112889082E071-7988
chr10112905736112906481E0718666
chr10112905736112906481E0728666
chr10112873507112873640E074-23430
chr10112869739112869843E081-27227
chr10112870189112870243E081-26827
chr10112870574112871003E081-26067
chr10112871091112871209E081-25861
chr10112870574112871003E082-26067
chr10112946226112946468E08249156
chr10112946551112946618E08249481