rs7075856

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0202 (6053/29956,GnomAD)
A=0172 (5033/29118,TOPMED)
A=0185 (924/5008,1000G)
A=0203 (784/3854,ALSPAC)
A=0203 (754/3708,TWINSUK)
chr10:98329453 (GRCh38.p7) (10q24.2)
AD
GWASdb2
1   publication(s)
See rs on genome
145 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.98329453C>A
GRCh37.p13 chr 10NC_000010.10:g.100089210C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.878A=0.122
1000GenomesAmericanSub694C=0.840A=0.160
1000GenomesEast AsianSub1008C=0.814A=0.186
1000GenomesEuropeSub1006C=0.771A=0.229
1000GenomesGlobalStudy-wide5008C=0.815A=0.185
1000GenomesSouth AsianSub978C=0.760A=0.240
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.797A=0.203
The Genome Aggregation DatabaseAfricanSub8722C=0.873A=0.127
The Genome Aggregation DatabaseAmericanSub836C=0.840A=0.160
The Genome Aggregation DatabaseEast AsianSub1620C=0.798A=0.202
The Genome Aggregation DatabaseEuropeSub18476C=0.759A=0.240
The Genome Aggregation DatabaseGlobalStudy-wide29956C=0.797A=0.202
The Genome Aggregation DatabaseOtherSub302C=0.880A=0.120
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.827A=0.172
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.797A=0.203
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs70758560.000798alcohol dependence21314694

eQTL of rs7075856 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7075856 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10100055000100055050E067-34160
chr10100055113100055559E067-33651
chr10100055708100056002E067-33208
chr10100100748100101074E06711538
chr10100127376100128333E06738166
chr10100086041100086226E068-2984
chr10100086304100086743E068-2467
chr10100100748100101074E06811538
chr10100125624100126239E06836414
chr10100126393100126485E06837183
chr10100126797100126847E06837587
chr10100126954100127086E06837744
chr10100127149100127199E06837939
chr10100127376100128333E06838166
chr10100055000100055050E069-34160
chr10100055113100055559E069-33651
chr10100125624100126239E06936414
chr10100126393100126485E06937183
chr10100127149100127199E06937939
chr10100127376100128333E06938166
chr10100128512100128603E06939302
chr10100128632100129147E06939422
chr10100129180100129489E06939970
chr10100129578100129757E06940368
chr10100055000100055050E070-34160
chr10100055113100055559E070-33651
chr10100059015100059065E070-30145
chr10100059097100059149E070-30061
chr10100059220100059384E070-29826
chr10100059516100059566E070-29644
chr10100059764100059804E070-29406
chr10100059985100060035E070-29175
chr10100060238100060278E070-28932
chr10100060383100060433E070-28777
chr10100068453100069826E070-19384
chr10100086041100086226E070-2984
chr10100086304100086743E070-2467
chr10100087087100087176E070-2034
chr10100087250100087333E070-1877
chr10100126797100126847E07037587
chr10100126954100127086E07037744
chr10100127149100127199E07037939
chr10100127376100128333E07038166
chr10100055113100055559E071-33651
chr10100055708100056002E071-33208
chr10100068453100069826E071-19384
chr10100100748100101074E07111538
chr10100125624100126239E07136414
chr10100126393100126485E07137183
chr10100126797100126847E07137587
chr10100126954100127086E07137744
chr10100127149100127199E07137939
chr10100128512100128603E07139302
chr10100128632100129147E07139422
chr10100129180100129489E07139970
chr10100129578100129757E07140368
chr10100129764100129804E07140554
chr10100133931100134788E07144721
chr10100068453100069826E072-19384
chr10100100748100101074E07211538
chr10100120784100121681E07231574
chr10100125624100126239E07236414
chr10100126393100126485E07237183
chr10100126797100126847E07237587
chr10100126954100127086E07237744
chr10100127149100127199E07237939
chr10100128512100128603E07239302
chr10100128632100129147E07239422
chr10100129180100129489E07239970
chr10100129578100129757E07240368
chr10100054129100054384E073-34826
chr10100054505100054593E073-34617
chr10100055000100055050E073-34160
chr10100055113100055559E073-33651
chr10100055708100056002E073-33208
chr10100120784100121681E07331574
chr10100127376100128333E07338166
chr10100086041100086226E074-2984
chr10100086304100086743E074-2467
chr10100120784100121681E07431574
chr10100125624100126239E07436414
chr10100126393100126485E07437183
chr10100126797100126847E07437587
chr10100126954100127086E07437744
chr10100127149100127199E07437939
chr10100128512100128603E07439302
chr10100128632100129147E07439422
chr10100129180100129489E07439970
chr10100129578100129757E07440368
chr10100054129100054384E081-34826
chr10100055113100055559E081-33651
chr10100055708100056002E081-33208
chr10100056144100056633E081-32577
chr10100056684100056805E081-32405
chr10100059516100059566E081-29644
chr10100059764100059804E081-29406
chr10100059985100060035E081-29175
chr10100061825100062112E081-27098
chr10100062164100062214E081-26996
chr10100062407100062480E081-26730
chr10100062570100062735E081-26475
chr10100062815100062967E081-26243
chr10100067732100068281E081-20929
chr10100068453100069826E081-19384
chr10100069899100070009E081-19201
chr10100070226100070322E081-18888
chr10100070721100070833E081-18377
chr10100079677100079760E081-9450
chr10100086041100086226E081-2984
chr10100086304100086743E081-2467
chr10100087087100087176E081-2034
chr10100090898100091078E0811688
chr10100091275100091338E0812065
chr10100098669100098856E0819459
chr10100098862100099140E0819652
chr10100099511100100675E08110301
chr10100100748100101074E08111538
chr10100101211100101346E08112001
chr10100101360100101524E08112150
chr10100126393100126485E08137183
chr10100126797100126847E08137587
chr10100126954100127086E08137744
chr10100127149100127199E08137939
chr10100127376100128333E08138166
chr10100129578100129757E08140368
chr10100129764100129804E08140554
chr10100054505100054593E082-34617
chr10100055000100055050E082-34160
chr10100055113100055559E082-33651
chr10100059516100059566E082-29644
chr10100060238100060278E082-28932
chr10100060383100060433E082-28777
chr10100068453100069826E082-19384
chr10100069899100070009E082-19201
chr10100070226100070322E082-18888
chr10100086041100086226E082-2984
chr10100086304100086743E082-2467
chr10100099511100100675E08210301
chr10100100748100101074E08211538
chr10100101211100101346E08212001
chr10100101360100101524E08212150
chr10100126954100127086E08237744
chr10100127149100127199E08237939
chr10100127376100128333E08238166
chr10100136156100136221E08246946