rs7090464

Homo sapiens
A>G / A>T
ZNF488 : 2KB Upstream Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0078 (2346/29960,GnomAD)
C=0076 (2217/29118,TOPMED)
C=0199 (997/5008,1000G)
C=0087 (336/3854,ALSPAC)
C=0088 (327/3708,TWINSUK)
chr10:47385686 (GRCh38.p7) (10q11.22)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.47385686A>G
GRCh38.p7 chr 10NC_000010.11:g.47385686A>T
GRCh37.p13 chr 10 fix patch HG1211_PATCHNW_003871068.1:g.1656801A>G
GRCh37.p13 chr 10 fix patch HG1211_PATCHNW_003871068.1:g.1656801A>T
GRCh37.p13 chr 10NC_000010.10:g.48353676T>C
GRCh37.p13 chr 10NC_000010.10:g.48353676T>A

Gene: ZNF488, zinc finger protein 488(minus strand): 2KB Upstream Variant

Molecule type Change Amino acid[Codon] SO Term
ZNF488 transcriptNM_153034.2:c.N/AUpstream Transcript Variant
ZNF488 transcript variant X4XM_006717617.3:c.N/AUpstream Transcript Variant
ZNF488 transcript variant X1XM_011539244.2:c.N/AUpstream Transcript Variant
ZNF488 transcript variant X2XM_017015642.1:c.N/AUpstream Transcript Variant
ZNF488 transcript variant X2XM_017015643.1:c.N/AUpstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.990G=0.010
1000GenomesAmericanSub694A=0.670G=0.330
1000GenomesEast AsianSub1008A=0.632G=0.368
1000GenomesEuropeSub1006A=0.920G=0.080
1000GenomesGlobalStudy-wide5008A=0.801G=0.199
1000GenomesSouth AsianSub978A=0.690G=0.310
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.913G=0.087
The Genome Aggregation DatabaseAfricanSub8722A=0.980G=0.020
The Genome Aggregation DatabaseAmericanSub838A=0.680G=0.320
The Genome Aggregation DatabaseEast AsianSub1616A=0.637G=0.363
The Genome Aggregation DatabaseEuropeSub18484A=0.931G=0.068
The Genome Aggregation DatabaseGlobalStudy-wide29960A=0.921G=0.078
The Genome Aggregation DatabaseOtherSub300A=0.850G=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.923G=0.076
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.912G=0.088
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs70904640.000729alcohol dependence21314694

eQTL of rs7090464 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7090464 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.