rs7092048

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0110 (3315/29926,GnomAD)
T==0094 (2738/29118,TOPMED)
T==0084 (422/5008,1000G)
T==0152 (587/3854,ALSPAC)
T==0157 (584/3708,TWINSUK)
chr10:109437972 (GRCh38.p7) (10q25.1)
AD
GWASdb2
1   publication(s)
See rs on genome
10 Enhancers around
7 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.109437972T>C
GRCh37.p13 chr 10NC_000010.10:g.111197730T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.012C=0.988
1000GenomesAmericanSub694T=0.100C=0.900
1000GenomesEast AsianSub1008T=0.049C=0.951
1000GenomesEuropeSub1006T=0.133C=0.867
1000GenomesGlobalStudy-wide5008T=0.084C=0.916
1000GenomesSouth AsianSub978T=0.160C=0.840
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.152C=0.848
The Genome Aggregation DatabaseAfricanSub8722T=0.033C=0.967
The Genome Aggregation DatabaseAmericanSub834T=0.150C=0.850
The Genome Aggregation DatabaseEast AsianSub1598T=0.046C=0.954
The Genome Aggregation DatabaseEuropeSub18470T=0.151C=0.849
The Genome Aggregation DatabaseGlobalStudy-wide29926T=0.110C=0.889
The Genome Aggregation DatabaseOtherSub302T=0.150C=0.850
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.094C=0.906
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.157C=0.843
PMID Title Author Journal
23089632A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.Wang JCMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs70920482.33E-06alcohol dependence23089632

eQTL of rs7092048 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7092048 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10111186807111187200E070-10530
chr10111235463111235889E07037733
chr10111186807111187200E071-10530
chr10111236097111236176E08138367
chr10111234508111234609E08236778
chr10111234618111234925E08236888
chr10111234931111235063E08237201
chr10111235322111235372E08237592
chr10111235463111235889E08237733
chr10111236097111236176E08238367




Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr10111216023111217170E06818293
chr10111216023111217170E07018293
chr10111216023111217170E07118293
chr10111216023111217170E07218293
chr10111216023111217170E07318293
chr10111216023111217170E08218293
chr10111217287111217350E08219557