rs7097645

Homo sapiens
A>G
HSPA12A : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0465 (13917/29918,GnomAD)
A==0458 (13336/29118,TOPMED)
A==0464 (2326/5008,1000G)
chr10:116800966 (GRCh38.p7) (10q25.3)
AD
GWASdb2
1   publication(s)
See rs on genome
155 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.116800966A>G
GRCh37.p13 chr 10NC_000010.10:g.118560477A>G

Gene: HSPA12A, heat shock protein family A (Hsp70) member 12A(minus strand)

Molecule type Change Amino acid[Codon] SO Term
HSPA12A transcript variant 2NM_025015.2:c.N/AGenic Upstream Transcript Variant
HSPA12A transcript variant X1XM_005269672.3:c.N/AIntron Variant
HSPA12A transcript variant X3XM_005269673.4:c.N/AIntron Variant
HSPA12A transcript variant X1XM_011539579.2:c.N/AIntron Variant
HSPA12A transcript variant X3XM_011539580.2:c.N/AGenic Upstream Transcript Variant
HSPA12A transcript variant X5XM_017016032.1:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.551G=0.449
1000GenomesAmericanSub694A=0.440G=0.560
1000GenomesEast AsianSub1008A=0.389G=0.611
1000GenomesEuropeSub1006A=0.434G=0.566
1000GenomesGlobalStudy-wide5008A=0.464G=0.536
1000GenomesSouth AsianSub978A=0.470G=0.530
The Genome Aggregation DatabaseAfricanSub8698A=0.521G=0.479
The Genome Aggregation DatabaseAmericanSub836A=0.350G=0.650
The Genome Aggregation DatabaseEast AsianSub1616A=0.351G=0.649
The Genome Aggregation DatabaseEuropeSub18468A=0.454G=0.545
The Genome Aggregation DatabaseGlobalStudy-wide29918A=0.465G=0.534
The Genome Aggregation DatabaseOtherSub300A=0.410G=0.590
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.458G=0.542
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs70976450.000847alcohol dependence21314694

eQTL of rs7097645 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7097645 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10118512182118512434E067-48043
chr10118512573118512783E067-47694
chr10118515026118515072E067-45405
chr10118515441118515481E067-44996
chr10118515750118516143E067-44334
chr10118516443118516518E067-43959
chr10118521214118521289E067-39188
chr10118521500118521566E067-38911
chr10118521586118522058E067-38419
chr10118522508118522698E067-37779
chr10118522949118523773E067-36704
chr10118547265118548008E067-12469
chr10118548041118548111E067-12366
chr10118593478118594182E06733001
chr10118594420118594690E06733943
chr10118594701118594755E06734224
chr10118595345118596248E06734868
chr10118606812118606864E06746335
chr10118607120118607183E06746643
chr10118610140118610222E06749663
chr10118512182118512434E068-48043
chr10118512573118512783E068-47694
chr10118515441118515481E068-44996
chr10118515750118516143E068-44334
chr10118516443118516518E068-43959
chr10118516624118517085E068-43392
chr10118521500118521566E068-38911
chr10118521586118522058E068-38419
chr10118522508118522698E068-37779
chr10118522949118523773E068-36704
chr10118525225118525326E068-35151
chr10118525483118525576E068-34901
chr10118542847118543110E068-17367
chr10118546604118546822E068-13655
chr10118546828118547060E068-13417
chr10118562595118562635E0682118
chr10118563519118563599E0683042
chr10118563623118563777E0683146
chr10118596364118596730E06835887
chr10118512182118512434E069-48043
chr10118512573118512783E069-47694
chr10118515441118515481E069-44996
chr10118515750118516143E069-44334
chr10118516443118516518E069-43959
chr10118521214118521289E069-39188
chr10118521500118521566E069-38911
chr10118521586118522058E069-38419
chr10118522508118522698E069-37779
chr10118522949118523773E069-36704
chr10118525483118525576E069-34901
chr10118535615118535710E069-24767
chr10118548041118548111E069-12366
chr10118562595118562635E0692118
chr10118563135118563280E0692658
chr10118593478118594182E06933001
chr10118594420118594690E06933943
chr10118594701118594755E06934224
chr10118594825118595303E06934348
chr10118610140118610222E06949663
chr10118512573118512783E070-47694
chr10118513278118513562E070-46915
chr10118515750118516143E070-44334
chr10118516443118516518E070-43959
chr10118534349118534467E070-26010
chr10118534476118534660E070-25817
chr10118556204118556271E070-4206
chr10118563135118563280E0702658
chr10118593478118594182E07033001
chr10118594420118594690E07033943
chr10118594701118594755E07034224
chr10118594825118595303E07034348
chr10118595345118596248E07034868
chr10118607190118607244E07046713
chr10118607325118607439E07046848
chr10118607469118607539E07046992
chr10118610140118610222E07049663
chr10118512182118512434E071-48043
chr10118512573118512783E071-47694
chr10118513278118513562E071-46915
chr10118514761118514815E071-45662
chr10118515026118515072E071-45405
chr10118515441118515481E071-44996
chr10118515750118516143E071-44334
chr10118516443118516518E071-43959
chr10118516624118517085E071-43392
chr10118521214118521289E071-39188
chr10118521500118521566E071-38911
chr10118521586118522058E071-38419
chr10118522508118522698E071-37779
chr10118522949118523773E071-36704
chr10118524082118524146E071-36331
chr10118563135118563280E0712658
chr10118563519118563599E0713042
chr10118593478118594182E07133001
chr10118594420118594690E07133943
chr10118594701118594755E07134224
chr10118512182118512434E072-48043
chr10118512573118512783E072-47694
chr10118513278118513562E072-46915
chr10118515441118515481E072-44996
chr10118515750118516143E072-44334
chr10118516443118516518E072-43959
chr10118521214118521289E072-39188
chr10118521500118521566E072-38911
chr10118521586118522058E072-38419
chr10118522508118522698E072-37779
chr10118522949118523773E072-36704
chr10118525483118525576E072-34901
chr10118548041118548111E072-12366
chr10118562595118562635E0722118
chr10118563135118563280E0722658
chr10118593478118594182E07233001
chr10118594420118594690E07233943
chr10118594701118594755E07234224
chr10118594825118595303E07234348
chr10118595345118596248E07234868
chr10118610140118610222E07249663
chr10118512182118512434E073-48043
chr10118512573118512783E073-47694
chr10118513278118513562E073-46915
chr10118516443118516518E073-43959
chr10118521586118522058E073-38419
chr10118522508118522698E073-37779
chr10118548041118548111E073-12366
chr10118595345118596248E07334868
chr10118610140118610222E07349663
chr10118610411118610451E07349934
chr10118512182118512434E074-48043
chr10118512573118512783E074-47694
chr10118514761118514815E074-45662
chr10118515026118515072E074-45405
chr10118515441118515481E074-44996
chr10118515750118516143E074-44334
chr10118516443118516518E074-43959
chr10118516624118517085E074-43392
chr10118521500118521566E074-38911
chr10118521586118522058E074-38419
chr10118522508118522698E074-37779
chr10118522949118523773E074-36704
chr10118562595118562635E0742118
chr10118563135118563280E0742658
chr10118593478118594182E07433001
chr10118610140118610222E07449663
chr10118515750118516143E081-44334
chr10118546424118546581E081-13896
chr10118546604118546822E081-13655
chr10118546828118547060E081-13417
chr10118547265118548008E081-12469
chr10118548041118548111E081-12366
chr10118562595118562635E0812118
chr10118595345118596248E08134868
chr10118610140118610222E08149663
chr10118610411118610451E08149934
chr10118546604118546822E082-13655
chr10118546828118547060E082-13417










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr10118607573118610012E06747096
chr10118607573118610012E06847096
chr10118607573118610012E06947096
chr10118607573118610012E07047096
chr10118607573118610012E07147096
chr10118607573118610012E07247096
chr10118607573118610012E07347096
chr10118607573118610012E07447096
chr10118607573118610012E08147096
chr10118607573118610012E08247096