rs7099076

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0255 (7641/29900,GnomAD)
C=0223 (6506/29118,TOPMED)
C=0206 (1031/5008,1000G)
C=0328 (1265/3854,ALSPAC)
C=0357 (1324/3708,TWINSUK)
chr10:129974707 (GRCh38.p7) (10q26.3)
AD
GWASdb2
1   publication(s)
See rs on genome
28 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.129974707T>C
GRCh37.p13 chr 10NC_000010.10:g.131772971T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.880C=0.120
1000GenomesAmericanSub694T=0.720C=0.280
1000GenomesEast AsianSub1008T=0.821C=0.179
1000GenomesEuropeSub1006T=0.675C=0.325
1000GenomesGlobalStudy-wide5008T=0.794C=0.206
1000GenomesSouth AsianSub978T=0.820C=0.180
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.672C=0.328
The Genome Aggregation DatabaseAfricanSub8714T=0.859C=0.141
The Genome Aggregation DatabaseAmericanSub836T=0.740C=0.260
The Genome Aggregation DatabaseEast AsianSub1622T=0.809C=0.191
The Genome Aggregation DatabaseEuropeSub18426T=0.685C=0.314
The Genome Aggregation DatabaseGlobalStudy-wide29900T=0.744C=0.255
The Genome Aggregation DatabaseOtherSub302T=0.720C=0.280
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.776C=0.223
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.643C=0.357
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs70990760.00041alcohol dependence(early age of onset)20201924
rs70990760.00044alcohol dependence20201924

eQTL of rs7099076 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7099076 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10131730812131730874E070-42097
chr10131731434131731711E070-41260
chr10131731837131731901E070-41070
chr10131731902131731952E070-41019
chr10131732182131732232E070-40739
chr10131732716131733018E070-39953
chr10131733019131733071E070-39900
chr10131747644131747897E070-25074
chr10131747915131748676E070-24295
chr10131748699131749874E070-23097
chr10131749955131750168E070-22803
chr10131750237131751030E070-21941
chr10131730812131730874E081-42097
chr10131731434131731711E081-41260
chr10131748699131749874E081-23097
chr10131749955131750168E081-22803
chr10131812971131813345E08140000
chr10131813350131813446E08140379
chr10131818605131818686E08145634
chr10131818796131820188E08145825
chr10131820217131820625E08147246
chr10131820660131820721E08147689
chr10131820830131822134E08147859
chr10131731434131731711E082-41260
chr10131747644131747897E082-25074
chr10131818796131820188E08245825
chr10131820217131820625E08247246
chr10131820660131820721E08247689