rs7100211

Homo sapiens
T>C
LOC105376360 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0224 (6716/29948,GnomAD)
C=0258 (7522/29118,TOPMED)
C=0274 (1373/5008,1000G)
C=0164 (631/3854,ALSPAC)
C=0166 (614/3708,TWINSUK)
chr10:3685755 (GRCh38.p7) (10p15.2)
ND
GWASdb2
1   publication(s)
See rs on genome
25 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.3685755T>C
GRCh37.p13 chr 10NC_000010.10:g.3727947T>C

Gene: LOC105376360, uncharacterized LOC105376360(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105376360 transcriptNR_131187.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.619C=0.381
1000GenomesAmericanSub694T=0.760C=0.240
1000GenomesEast AsianSub1008T=0.593C=0.407
1000GenomesEuropeSub1006T=0.832C=0.168
1000GenomesGlobalStudy-wide5008T=0.726C=0.274
1000GenomesSouth AsianSub978T=0.870C=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.836C=0.164
The Genome Aggregation DatabaseAfricanSub8714T=0.655C=0.345
The Genome Aggregation DatabaseAmericanSub834T=0.760C=0.240
The Genome Aggregation DatabaseEast AsianSub1616T=0.613C=0.387
The Genome Aggregation DatabaseEuropeSub18484T=0.847C=0.152
The Genome Aggregation DatabaseGlobalStudy-wide29948T=0.775C=0.224
The Genome Aggregation DatabaseOtherSub300T=0.790C=0.210
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.741C=0.258
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.834C=0.166
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs71002110.000634nicotine dependence17158188

eQTL of rs7100211 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7100211 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1036984833698835E070-29112
chr1036989223698991E070-28956
chr1037236133723696E070-4251
chr1037237403724269E070-3678
chr1037419003741960E07413953
chr1037419803742061E07414033
chr1036788283679334E081-48613
chr1036795493679619E081-48328
chr1036905233690653E081-37294
chr1036906613690768E081-37179
chr1037356613735788E0817714
chr1037359513736192E0818004
chr1037583273758704E08130380
chr1037587713758873E08130824
chr1037625653763269E08134618
chr1037632733763469E08135326
chr1037653033765528E08137356
chr1037659083766434E08137961
chr1037665613766663E08138614
chr1037583273758704E08230380
chr1037625653763269E08234618
chr1037632733763469E08235326
chr1037635743763661E08235627
chr1037642523764334E08236305
chr1037643833764608E08236436