rs7108752

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0253 (7576/29938,GnomAD)
A==0271 (7915/29118,TOPMED)
A==0260 (1304/5008,1000G)
A==0203 (781/3854,ALSPAC)
A==0193 (714/3708,TWINSUK)
chr11:13218012 (GRCh38.p7) (11p15.3)
AD
GWASdb2
2   publication(s)
See rs on genome
130 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.13218012A>G
GRCh37.p13 chr 11NC_000011.9:g.13239559A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.338G=0.662
1000GenomesAmericanSub694A=0.290G=0.710
1000GenomesEast AsianSub1008A=0.186G=0.814
1000GenomesEuropeSub1006A=0.245G=0.755
1000GenomesGlobalStudy-wide5008A=0.260G=0.740
1000GenomesSouth AsianSub978A=0.230G=0.770
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.203G=0.797
The Genome Aggregation DatabaseAfricanSub8702A=0.302G=0.698
The Genome Aggregation DatabaseAmericanSub836A=0.350G=0.650
The Genome Aggregation DatabaseEast AsianSub1620A=0.158G=0.842
The Genome Aggregation DatabaseEuropeSub18478A=0.234G=0.766
The Genome Aggregation DatabaseGlobalStudy-wide29938A=0.253G=0.746
The Genome Aggregation DatabaseOtherSub302A=0.250G=0.750
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.271G=0.728
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.193G=0.807
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
21709609Circadian clock gene polymorphisms and sleep-wake disturbance in Alzheimer disease.Yesavage JAAm J Geriatr Psychiatry

P-Value

SNP ID p-value Traits Study
rs71087520.00032alcohol dependence20201924

eQTL of rs7108752 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7108752 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr111318960113189651E067-49908
chr111318972613190324E067-49235
chr111322875313228821E067-10738
chr111322883313228910E067-10649
chr111322892813230199E067-9360
chr111323021413230357E067-9202
chr111323039913230476E067-9083
chr111323057713230800E067-8759
chr111318960113189651E068-49908
chr111318972613190324E068-49235
chr111319034113190874E068-48685
chr111322696313227434E068-12125
chr111322746013227670E068-11889
chr111322771913227893E068-11666
chr111322792413228022E068-11537
chr111322802613228084E068-11475
chr111322851513228583E068-10976
chr111322875313228821E068-10738
chr111322883313228910E068-10649
chr111323057713230800E068-8759
chr111323085513230949E068-8610
chr111323113013231219E068-8340
chr111323128913231349E068-8210
chr111323139113231521E068-8038
chr111323745913238679E068-880
chr111325923713259301E06819678
chr111325933413259711E06819775
chr111318960113189651E069-49908
chr111318972613190324E069-49235
chr111322621113226261E069-13298
chr111322687013226924E069-12635
chr111322696313227434E069-12125
chr111322746013227670E069-11889
chr111322771913227893E069-11666
chr111322851513228583E069-10976
chr111322875313228821E069-10738
chr111322883313228910E069-10649
chr111322892813230199E069-9360
chr111323021413230357E069-9202
chr111323039913230476E069-9083
chr111323057713230800E069-8759
chr111324380913244212E0694250
chr111324458613245011E0695027
chr111324517213245305E0695613
chr111325115713252322E06911598
chr111318960113189651E070-49908
chr111318972613190324E070-49235
chr111322687013226924E070-12635
chr111322696313227434E070-12125
chr111322746013227670E070-11889
chr111322771913227893E070-11666
chr111322792413228022E070-11537
chr111322892813230199E070-9360
chr111323021413230357E070-9202
chr111323039913230476E070-9083
chr111323057713230800E070-8759
chr111323085513230949E070-8610
chr111324181513241919E0702256
chr111324195613242003E0702397
chr111324458613245011E0705027
chr111324517213245305E0705613
chr111325019913250435E07010640
chr111325052313251129E07010964
chr111325115713252322E07011598
chr111318960113189651E071-49908
chr111318972613190324E071-49235
chr111322687013226924E071-12635
chr111322696313227434E071-12125
chr111322746013227670E071-11889
chr111322771913227893E071-11666
chr111322792413228022E071-11537
chr111322892813230199E071-9360
chr111323021413230357E071-9202
chr111323039913230476E071-9083
chr111323745913238679E071-880
chr111325115713252322E07111598
chr111322696313227434E072-12125
chr111322746013227670E072-11889
chr111322771913227893E072-11666
chr111323021413230357E072-9202
chr111323039913230476E072-9083
chr111323057713230800E072-8759
chr111323181813231933E072-7626
chr111325115713252322E07211598
chr111318960113189651E073-49908
chr111318972613190324E073-49235
chr111322696313227434E073-12125
chr111322746013227670E073-11889
chr111322875313228821E073-10738
chr111322883313228910E073-10649
chr111322892813230199E073-9360
chr111323021413230357E073-9202
chr111323039913230476E073-9083
chr111318960113189651E074-49908
chr111318972613190324E074-49235
chr111322687013226924E074-12635
chr111322696313227434E074-12125
chr111322746013227670E074-11889
chr111322892813230199E074-9360
chr111323021413230357E074-9202
chr111323039913230476E074-9083
chr111323057713230800E074-8759
chr111322696313227434E081-12125
chr111322746013227670E081-11889
chr111322771913227893E081-11666
chr111322792413228022E081-11537
chr111322892813230199E081-9360
chr111323021413230357E081-9202
chr111323039913230476E081-9083
chr111323057713230800E081-8759
chr111324124413241294E0811685
chr111324380913244212E0814250
chr111324458613245011E0815027
chr111324517213245305E0815613
chr111325019913250435E08110640
chr111325052313251129E08110964
chr111325115713252322E08111598
chr111322696313227434E082-12125
chr111322746013227670E082-11889
chr111322771913227893E082-11666
chr111323021413230357E082-9202
chr111323039913230476E082-9083
chr111323057713230800E082-8759
chr111323171213231809E082-7750
chr111323181813231933E082-7626
chr111324380913244212E0824250
chr111324458613245011E0825027
chr111325052313251129E08210964
chr111325115713252322E08211598
chr111325629313256373E08216734










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr111325981513259900E06820256