rs7110424

Organism: Homo sapiens

Alleles: G>T

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0204 (6125/29908,GnomAD)
G==0219 (6398/29118,TOPMED)
G==0280 (1404/5008,1000G)
G==0113 (434/3854,ALSPAC)
G==0120 (444/3708,TWINSUK)

Position: chr11:102552935 (GRCh38.p7) (11q22.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 43 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 11	NC_000011.10:g.102552935G>T
GRCh37.p13 chr 11	NC_000011.9:g.102423666G>T

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.353	T=0.647
1000Genomes	American	Sub	694	G=0.240	T=0.760
1000Genomes	East Asian	Sub	1008	G=0.403	T=0.597
1000Genomes	Europe	Sub	1006	G=0.133	T=0.867
1000Genomes	Global	Study-wide	5008	G=0.280	T=0.720
1000Genomes	South Asian	Sub	978	G=0.240	T=0.760
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.113	T=0.887
The Genome Aggregation Database	African	Sub	8684	G=0.307	T=0.693
The Genome Aggregation Database	American	Sub	838	G=0.210	T=0.790
The Genome Aggregation Database	East Asian	Sub	1616	G=0.425	T=0.575
The Genome Aggregation Database	Europe	Sub	18472	G=0.138	T=0.861
The Genome Aggregation Database	Global	Study-wide	29908	G=0.204	T=0.795
The Genome Aggregation Database	Other	Sub	298	G=0.110	T=0.890
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.219	T=0.780
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.120	T=0.880

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs7110424	0.000862	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

There is no significant Hi-C chromatin interaction data for this SNP.

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr11	102421851	102421950	E067	-1716
chr11	102422090	102422206	E067	-1460
chr11	102422286	102422336	E067	-1330
chr11	102399214	102399806	E068	-23860
chr11	102399910	102400075	E068	-23591
chr11	102421851	102421950	E068	-1716
chr11	102472204	102472411	E068	48538
chr11	102472537	102472591	E068	48871
chr11	102473105	102473213	E068	49439
chr11	102421851	102421950	E069	-1716
chr11	102422090	102422206	E069	-1460
chr11	102422286	102422336	E069	-1330
chr11	102472204	102472411	E069	48538
chr11	102472537	102472591	E069	48871
chr11	102473105	102473213	E069	49439
chr11	102399214	102399806	E071	-23860
chr11	102399910	102400075	E071	-23591
chr11	102400149	102400201	E071	-23465
chr11	102401019	102401066	E071	-22600
chr11	102422090	102422206	E071	-1460
chr11	102422286	102422336	E071	-1330
chr11	102472537	102472591	E071	48871
chr11	102473105	102473213	E071	49439
chr11	102399910	102400075	E072	-23591
chr11	102401019	102401066	E072	-22600
chr11	102421851	102421950	E072	-1716
chr11	102422090	102422206	E072	-1460
chr11	102422286	102422336	E072	-1330
chr11	102473105	102473213	E072	49439
chr11	102421851	102421950	E073	-1716
chr11	102422090	102422206	E073	-1460
chr11	102422286	102422336	E073	-1330
chr11	102472537	102472591	E073	48871
chr11	102399081	102399137	E074	-24529
chr11	102399214	102399806	E074	-23860
chr11	102399910	102400075	E074	-23591
chr11	102400149	102400201	E074	-23465
chr11	102421851	102421950	E074	-1716
chr11	102422090	102422206	E074	-1460
chr11	102422286	102422336	E074	-1330
chr11	102472204	102472411	E074	48538
chr11	102472537	102472591	E074	48871
chr11	102473105	102473213	E074	49439