rs7111117

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0035 (1052/29984,GnomAD)
C=0034 (992/29118,TOPMED)
C=0058 (292/5008,1000G)
C=0042 (161/3854,ALSPAC)
C=0043 (160/3708,TWINSUK)
chr11:39968412 (GRCh38.p7) (11p12)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.39968412T>C
GRCh37.p13 chr 11NC_000011.9:g.39989962T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.980C=0.020
1000GenomesAmericanSub694T=0.910C=0.090
1000GenomesEast AsianSub1008T=0.918C=0.082
1000GenomesEuropeSub1006T=0.965C=0.035
1000GenomesGlobalStudy-wide5008T=0.942C=0.058
1000GenomesSouth AsianSub978T=0.910C=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.958C=0.042
The Genome Aggregation DatabaseAfricanSub8724T=0.980C=0.020
The Genome Aggregation DatabaseAmericanSub838T=0.910C=0.090
The Genome Aggregation DatabaseEast AsianSub1622T=0.916C=0.084
The Genome Aggregation DatabaseEuropeSub18498T=0.964C=0.035
The Genome Aggregation DatabaseGlobalStudy-wide29984T=0.964C=0.035
The Genome Aggregation DatabaseOtherSub302T=0.970C=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.965C=0.034
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.957C=0.043
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs71111170.0002alcohol dependence20201924

eQTL of rs7111117 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7111117 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.