rs712241

Homo sapiens
G>C / G>T
None
Check p-value
SNV (Single Nucleotide Variation)
G==0444 (13275/29888,GnomAD)
G==0440 (12836/29118,TOPMED)
G==0392 (1962/5008,1000G)
G==0454 (1748/3854,ALSPAC)
G==0462 (1713/3708,TWINSUK)
chr6:153972045 (GRCh38.p7) (6q25.2)
ND
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.153972045G>C
GRCh38.p7 chr 6NC_000006.12:g.153972045G>T
GRCh37.p13 chr 6NC_000006.11:g.154293180G>C
GRCh37.p13 chr 6NC_000006.11:g.154293180G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.412T=0.588
1000GenomesAmericanSub694G=0.450T=0.550
1000GenomesEast AsianSub1008G=0.364T=0.636
1000GenomesEuropeSub1006G=0.453T=0.547
1000GenomesGlobalStudy-wide5008G=0.392T=0.608
1000GenomesSouth AsianSub978G=0.290T=0.710
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.454T=0.546
The Genome Aggregation DatabaseAfricanSub8690G=0.430T=0.570
The Genome Aggregation DatabaseAmericanSub832G=0.460T=0.54,
The Genome Aggregation DatabaseEast AsianSub1614G=0.411T=0.589
The Genome Aggregation DatabaseEuropeSub18450G=0.453T=0.546
The Genome Aggregation DatabaseGlobalStudy-wide29888G=0.444T=0.555
The Genome Aggregation DatabaseOtherSub302G=0.410T=0.59,
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.440T=0.559
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.462T=0.538
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs7122410.000824nicotine dependence17158188

eQTL of rs712241 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs712241 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr67528740875287717E069-9625
chr67528800375288468E069-8874