rs7128824

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0427 (12778/29914,GnomAD)
C=0391 (11404/29118,TOPMED)
C=0454 (2274/5008,1000G)
A==0476 (1836/3854,ALSPAC)
A==0470 (1741/3708,TWINSUK)
chr11:116261235 (GRCh38.p7) (11q23.3)
AD
GWASdb2
1   publication(s)
See rs on genome
180 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.116261235A>C
GRCh37.p13 chr 11NC_000011.9:g.116131952A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.797C=0.203
1000GenomesAmericanSub694A=0.590C=0.410
1000GenomesEast AsianSub1008A=0.486C=0.514
1000GenomesEuropeSub1006A=0.457C=0.543
1000GenomesGlobalStudy-wide5008A=0.546C=0.454
1000GenomesSouth AsianSub978A=0.330C=0.670
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.476C=0.524
The Genome Aggregation DatabaseAfricanSub8688A=0.763C=0.237
The Genome Aggregation DatabaseAmericanSub838A=0.600C=0.400
The Genome Aggregation DatabaseEast AsianSub1616A=0.490C=0.510
The Genome Aggregation DatabaseEuropeSub18470A=0.489C=0.510
The Genome Aggregation DatabaseGlobalStudy-wide29914A=0.572C=0.427
The Genome Aggregation DatabaseOtherSub302A=0.520C=0.480
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.608C=0.391
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.470C=0.530
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs71288240.00015alcohol dependence(early age of onset)20201924
rs71288240.00021alcohol dependence20201924

eQTL of rs7128824 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7128824 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11116089825116089984E067-41968
chr11116095592116095644E067-36308
chr11116095694116095765E067-36187
chr11116095804116096349E067-35603
chr11116095592116095644E068-36308
chr11116095694116095765E068-36187
chr11116099906116101440E068-30512
chr11116127862116128078E068-3874
chr11116133891116134128E0681939
chr11116089720116089802E069-42150
chr11116089825116089984E069-41968
chr11116090062116090437E069-41515
chr11116095189116095526E069-36426
chr11116095592116095644E069-36308
chr11116095694116095765E069-36187
chr11116146992116148073E06915040
chr11116087692116088108E070-43844
chr11116090062116090437E070-41515
chr11116090459116090536E070-41416
chr11116094790116094855E070-37097
chr11116095037116095119E070-36833
chr11116095189116095526E070-36426
chr11116095592116095644E070-36308
chr11116095694116095765E070-36187
chr11116095804116096349E070-35603
chr11116096354116096463E070-35489
chr11116096588116096789E070-35163
chr11116099356116099477E070-32475
chr11116099519116099573E070-32379
chr11116099906116101440E070-30512
chr11116101508116101564E070-30388
chr11116101588116101684E070-30268
chr11116101846116101933E070-30019
chr11116102142116102668E070-29284
chr11116102787116102841E070-29111
chr11116103046116103101E070-28851
chr11116103133116103547E070-28405
chr11116103566116103710E070-28242
chr11116103799116103986E070-27966
chr11116104186116104374E070-27578
chr11116104419116104679E070-27273
chr11116113708116113782E070-18170
chr11116113863116113913E070-18039
chr11116113940116113990E070-17962
chr11116114823116114863E070-17089
chr11116114872116114984E070-16968
chr11116114994116115094E070-16858
chr11116115422116115658E070-16294
chr11116115669116115940E070-16012
chr11116120645116120695E070-11257
chr11116133279116133345E0701327
chr11116133426116133511E0701474
chr11116133516116133566E0701564
chr11116133891116134128E0701939
chr11116134195116134902E0702243
chr11116134996116135069E0703044
chr11116136393116136443E0704441
chr11116136598116136687E0704646
chr11116136712116136759E0704760
chr11116137006116137218E0705054
chr11116137366116137446E0705414
chr11116137818116137899E0705866
chr11116138000116138126E0706048
chr11116143100116143199E07011148
chr11116144276116144347E07012324
chr11116144512116144570E07012560
chr11116144870116144920E07012918
chr11116145010116145973E07013058
chr11116146041116146091E07014089
chr11116146122116146179E07014170
chr11116146455116146643E07014503
chr11116146827116146990E07014875
chr11116146992116148073E07015040
chr11116148123116148187E07016171
chr11116149494116149683E07017542
chr11116149740116149823E07017788
chr11116150195116150728E07018243
chr11116150970116151021E07019018
chr11116155376116155466E07023424
chr11116155756116156105E07023804
chr11116156163116156293E07024211
chr11116171030116171074E07039078
chr11116171148116171273E07039196
chr11116171617116171667E07039665
chr11116180926116181248E07048974
chr11116181557116181703E07049605
chr11116095037116095119E071-36833
chr11116095189116095526E071-36426
chr11116095592116095644E071-36308
chr11116095694116095765E071-36187
chr11116095804116096349E071-35603
chr11116095592116095644E072-36308
chr11116095694116095765E072-36187
chr11116095804116096349E072-35603
chr11116133891116134128E0721939
chr11116089720116089802E073-42150
chr11116089825116089984E073-41968
chr11116090062116090437E073-41515
chr11116090459116090536E073-41416
chr11116094656116094732E073-37220
chr11116094790116094855E073-37097
chr11116095189116095526E073-36426
chr11116095592116095644E073-36308
chr11116095694116095765E073-36187
chr11116136712116136759E0734760
chr11116146827116146990E07314875
chr11116146992116148073E07315040
chr11116090062116090437E081-41515
chr11116090459116090536E081-41416
chr11116095189116095526E081-36426
chr11116095592116095644E081-36308
chr11116095694116095765E081-36187
chr11116095804116096349E081-35603
chr11116096354116096463E081-35489
chr11116096588116096789E081-35163
chr11116099906116101440E081-30512
chr11116101508116101564E081-30388
chr11116101588116101684E081-30268
chr11116101846116101933E081-30019
chr11116120645116120695E081-11257
chr11116133426116133511E0811474
chr11116133516116133566E0811564
chr11116133891116134128E0811939
chr11116134195116134902E0812243
chr11116134996116135069E0813044
chr11116141106116141156E0819154
chr11116141462116141717E0819510
chr11116141981116142083E08110029
chr11116142476116142516E08110524
chr11116143100116143199E08111148
chr11116144276116144347E08112324
chr11116144512116144570E08112560
chr11116144870116144920E08112918
chr11116145010116145973E08113058
chr11116146041116146091E08114089
chr11116146122116146179E08114170
chr11116146455116146643E08114503
chr11116146827116146990E08114875
chr11116146992116148073E08115040
chr11116149494116149683E08117542
chr11116149740116149823E08117788
chr11116150195116150728E08118243
chr11116150970116151021E08119018
chr11116155376116155466E08123424
chr11116155756116156105E08123804
chr11116156163116156293E08124211
chr11116156915116156965E08124963
chr11116158328116158609E08126376
chr11116158700116158867E08126748
chr11116172408116172503E08140456
chr11116173358116173443E08141406
chr11116173500116174072E08141548
chr11116181557116181703E08149605
chr11116090062116090437E082-41515
chr11116090459116090536E082-41416
chr11116095189116095526E082-36426
chr11116095592116095644E082-36308
chr11116095694116095765E082-36187
chr11116095804116096349E082-35603
chr11116096354116096463E082-35489
chr11116096588116096789E082-35163
chr11116099906116101440E082-30512
chr11116101508116101564E082-30388
chr11116101588116101684E082-30268
chr11116133891116134128E0821939
chr11116134195116134902E0822243
chr11116136598116136687E0824646
chr11116136712116136759E0824760
chr11116137006116137218E0825054
chr11116137366116137446E0825414
chr11116144512116144570E08212560
chr11116144870116144920E08212918
chr11116145010116145973E08213058
chr11116146041116146091E08214089
chr11116146122116146179E08214170
chr11116155756116156105E08223804
chr11116156163116156293E08224211
chr11116156915116156965E08224963
chr11116173358116173443E08241406
chr11116173500116174072E08241548