rs7132890

Homo sapiens
G>A
LOC105369901 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0441 (13185/29840,GnomAD)
G==0460 (13417/29118,TOPMED)
G==0454 (2272/5008,1000G)
G==0369 (1424/3854,ALSPAC)
G==0370 (1373/3708,TWINSUK)
chr12:91966063 (GRCh38.p7) (12q21.33)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.91966063G>A
GRCh37.p13 chr 12NC_000012.11:g.92359839G>A

Gene: LOC105369901, uncharacterized LOC105369901(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105369901 transcript variant X2XR_001749253.1:n.N/AIntron Variant
LOC105369901 transcript variant X3XR_001749254.1:n.N/AIntron Variant
LOC105369901 transcript variant X4XR_001749255.1:n.N/AIntron Variant
LOC105369901 transcript variant X5XR_001749256.1:n.N/AIntron Variant
LOC105369901 transcript variant X1XR_945202.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.601A=0.399
1000GenomesAmericanSub694G=0.470A=0.530
1000GenomesEast AsianSub1008G=0.367A=0.633
1000GenomesEuropeSub1006G=0.393A=0.607
1000GenomesGlobalStudy-wide5008G=0.454A=0.546
1000GenomesSouth AsianSub978G=0.390A=0.610
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.369A=0.631
The Genome Aggregation DatabaseAfricanSub8686G=0.570A=0.430
The Genome Aggregation DatabaseAmericanSub838G=0.490A=0.510
The Genome Aggregation DatabaseEast AsianSub1612G=0.356A=0.644
The Genome Aggregation DatabaseEuropeSub18402G=0.388A=0.611
The Genome Aggregation DatabaseGlobalStudy-wide29840G=0.441A=0.558
The Genome Aggregation DatabaseOtherSub302G=0.320A=0.680
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.460A=0.539
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.370A=0.630
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs71328900.0006alcohol dependence20201924

eQTL of rs7132890 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7132890 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr129237908692379878E06719247
chr129237992792380182E06720088
chr129238034192380598E06720502
chr129237840992378679E06818570
chr129237992792380182E06820088
chr129238034192380598E06820502
chr129238185892382373E06822019
chr129238239492382520E06822555
chr129238254592382624E06822706
chr129238185892382373E06922019
chr129237726192377311E07017422
chr129237735892377408E07017519
chr129237741092377494E07017571
chr129237779292377997E07017953
chr129237822292378408E07018383
chr129237840992378679E07018570
chr129237889292379063E07019053
chr129237908692379878E07019247
chr129237992792380182E07020088
chr129238034192380598E07020502
chr129238073892380790E07020899
chr129238096992381013E07021130
chr129238135792381684E07021518
chr129238185892382373E07022019
chr129238239492382520E07022555
chr129238632392386403E07026484
chr129238650392386662E07026664
chr129238681492386867E07026975
chr129238723692387286E07027397
chr129238746892387522E07027629
chr129238759792387694E07027758
chr129238770392387822E07027864
chr129238793492388056E07028095
chr129238810792388176E07028268
chr129238932392389447E07029484
chr129239728392397343E07037444
chr129239749692397540E07037657
chr129239762792397712E07037788
chr129239772092397824E07037881
chr129237889292379063E07119053
chr129237908692379878E07119247
chr129237992792380182E07120088
chr129238034192380598E07120502
chr129238073892380790E07120899
chr129238096992381013E07121130
chr129238135792381684E07121518
chr129238185892382373E07222019
chr129238239492382520E07222555
chr129238254592382624E07222706
chr129237908692379878E07419247
chr129237992792380182E07420088
chr129238185892382373E07422019
chr129238239492382520E07422555
chr129238770392387822E08127864
chr129238793492388056E08128095
chr129238810792388176E08128268
chr129238135792381684E08221518