rs7137085

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0382 (11440/29874,GnomAD)
A=0416 (12139/29118,TOPMED)
A=0414 (2072/5008,1000G)
A=0337 (1297/3854,ALSPAC)
A=0344 (1274/3708,TWINSUK)
chr12:27932196 (GRCh38.p7) (12p11.22)
AD
GWASdb2
1   publication(s)
See rs on genome
10 Enhancers around
8 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.27932196G>A
GRCh37.p13 chr 12NC_000012.11:g.28085129G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.486A=0.514
1000GenomesAmericanSub694G=0.640A=0.360
1000GenomesEast AsianSub1008G=0.561A=0.439
1000GenomesEuropeSub1006G=0.641A=0.359
1000GenomesGlobalStudy-wide5008G=0.586A=0.414
1000GenomesSouth AsianSub978G=0.650A=0.350
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.663A=0.337
The Genome Aggregation DatabaseAfricanSub8698G=0.494A=0.506
The Genome Aggregation DatabaseAmericanSub838G=0.680A=0.320
The Genome Aggregation DatabaseEast AsianSub1600G=0.564A=0.436
The Genome Aggregation DatabaseEuropeSub18436G=0.677A=0.322
The Genome Aggregation DatabaseGlobalStudy-wide29874G=0.617A=0.382
The Genome Aggregation DatabaseOtherSub302G=0.600A=0.400
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.583A=0.416
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.656A=0.344
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs71370850.0000338alcoholismpha002893
rs71370850.000034alcohol dependence20201924
rs71370850.00037alcohol dependence(Early Onset)20201924

eQTL of rs7137085 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7137085 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr122806698528067039E070-18090
chr122806707428067199E070-17930
chr122812103128121390E07135902
chr122812103128121390E07235902
chr122805175828052738E081-32391
chr122806249028062540E081-22589
chr122806619728066351E081-18778
chr122811245028112535E08127321
chr122805175828052738E082-32391
chr122805279628052989E082-32140





Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr122812173628124907E06736607
chr122812173628124907E06836607
chr122812173628124907E06936607
chr122812173628124907E07136607
chr122812173628124907E07236607
chr122812173628124907E07336607
chr122812173628124907E07436607
chr122812173628124907E08236607