rs7141391

Homo sapiens
A>C / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
C=0382 (11441/29926,GnomAD)
C=0317 (9252/29118,TOPMED)
C=0258 (1291/5008,1000G)
C=0425 (1638/3854,ALSPAC)
C=0424 (1574/3708,TWINSUK)
chr14:20029578 (GRCh38.p7) (14q11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
84 Enhancers around
28 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.20029578A>C
GRCh38.p7 chr 14NC_000014.9:g.20029578A>T
GRCh37.p13 chr 14NC_000014.8:g.20497737A>C
GRCh37.p13 chr 14NC_000014.8:g.20497737A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.881C=0.111
1000GenomesAmericanSub694A=0.660C=0.34,
1000GenomesEast AsianSub1008A=0.749C=0.251
1000GenomesEuropeSub1006A=0.533C=0.467
1000GenomesGlobalStudy-wide5008A=0.740C=0.258
1000GenomesSouth AsianSub978A=0.810C=0.19,
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.575C=0.425
The Genome Aggregation DatabaseAfricanSub8716A=0.819C=0.175
The Genome Aggregation DatabaseAmericanSub834A=0.650C=0.35,
The Genome Aggregation DatabaseEast AsianSub1614A=0.754C=0.246
The Genome Aggregation DatabaseEuropeSub18460A=0.508C=0.491
The Genome Aggregation DatabaseGlobalStudy-wide29926A=0.615C=0.382
The Genome Aggregation DatabaseOtherSub302A=0.510C=0.49,
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.682C=0.317
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.576C=0.424
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs71413910.000279alcohol dependence20201924

eQTL of rs7141391 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7141391 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr146071888160718921E067-30262
chr146071906160719199E067-29984
chr146074022560740265E067-8918
chr146074066660740984E067-8199
chr146074105460741390E067-7793
chr146074274460742877E067-6306
chr146074290060743419E067-5764
chr146071888160718921E068-30262
chr146071906160719199E068-29984
chr146071922760719277E068-29906
chr146072100160721310E068-27873
chr146073981860739858E068-9325
chr146074022560740265E068-8918
chr146074066660740984E068-8199
chr146074105460741390E068-7793
chr146074195860742032E068-7151
chr146074204560742151E068-7032
chr146074274460742877E068-6306
chr146074440860744972E068-4211
chr146074508660745370E068-3813
chr146071888160718921E069-30262
chr146071906160719199E069-29984
chr146072358260723632E069-25551
chr146072388860723962E069-25221
chr146072468860724809E069-24374
chr146074022560740265E069-8918
chr146074066660740984E069-8199
chr146074105460741390E069-7793
chr146074290060743419E069-5764
chr146074508660745370E069-3813
chr146071888160718921E070-30262
chr146071906160719199E070-29984
chr146071922760719277E070-29906
chr146071427960714375E071-34808
chr146071888160718921E071-30262
chr146071906160719199E071-29984
chr146071922760719277E071-29906
chr146071946960719613E071-29570
chr146071964060719703E071-29480
chr146072011460720164E071-29019
chr146072026360720352E071-28831
chr146072041760720589E071-28594
chr146072082260720964E071-28219
chr146072321260723298E071-25885
chr146072358260723632E071-25551
chr146074066660740984E071-8199
chr146074105460741390E071-7793
chr146074195860742032E071-7151
chr146074204560742151E071-7032
chr146074229660742421E071-6762
chr146074261660742666E071-6517
chr146074274460742877E071-6306
chr146074290060743419E071-5764
chr146079292660793524E07143743
chr146079353560793614E07144352
chr146072468860724809E072-24374
chr146074022560740265E072-8918
chr146074066660740984E072-8199
chr146074274460742877E072-6306
chr146074290060743419E072-5764
chr146074508660745370E072-3813
chr146079529060795790E07246107
chr146071888160718921E073-30262
chr146071906160719199E073-29984
chr146071922760719277E073-29906
chr146072468860724809E073-24374
chr146073981860739858E073-9325
chr146074022560740265E073-8918
chr146074066660740984E073-8199
chr146074105460741390E073-7793
chr146071888160718921E074-30262
chr146071906160719199E074-29984
chr146072321260723298E074-25885
chr146072358260723632E074-25551
chr146072388860723962E074-25221
chr146073906360739241E074-9942
chr146074022560740265E074-8918
chr146074066660740984E074-8199
chr146074105460741390E074-7793
chr146074229660742421E074-6762
chr146074261660742666E074-6517
chr146074274460742877E074-6306
chr146079292660793524E07443743
chr146079353560793614E07444352








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr146071437760717585E067-31598
chr146079371660795180E06744533
chr146079756560798999E06748382
chr146071437760717585E068-31598
chr146079371660795180E06844533
chr146079756560798999E06848382
chr146071437760717585E069-31598
chr146079371660795180E06944533
chr146079756560798999E06948382
chr146071437760717585E070-31598
chr146079371660795180E07044533
chr146079756560798999E07048382
chr146071437760717585E071-31598
chr146079371660795180E07144533
chr146079756560798999E07148382
chr146071437760717585E072-31598
chr146079371660795180E07244533
chr146079756560798999E07248382
chr146071437760717585E073-31598
chr146079371660795180E07344533
chr146079756560798999E07348382
chr146071437760717585E074-31598
chr146079756560798999E07448382
chr146071437760717585E081-31598
chr146079371660795180E08144533
chr146071437760717585E082-31598
chr146079371660795180E08244533
chr146079756560798999E08248382