rs7144649

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0383 (11481/29934,GnomAD)
G==0485 (14134/29118,TOPMED)
G==0465 (2329/5008,1000G)
G==0217 (838/3854,ALSPAC)
G==0224 (830/3708,TWINSUK)
chr14:57355498 (GRCh38.p7) (14q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Enhancers around
20 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.57355498G>A
GRCh37.p13 chr 14NC_000014.8:g.57822216G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.909A=0.091
1000GenomesAmericanSub694G=0.350A=0.650
1000GenomesEast AsianSub1008G=0.279A=0.721
1000GenomesEuropeSub1006G=0.219A=0.781
1000GenomesGlobalStudy-wide5008G=0.465A=0.535
1000GenomesSouth AsianSub978G=0.390A=0.610
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.217A=0.783
The Genome Aggregation DatabaseAfricanSub8696G=0.797A=0.203
The Genome Aggregation DatabaseAmericanSub836G=0.310A=0.690
The Genome Aggregation DatabaseEast AsianSub1620G=0.252A=0.748
The Genome Aggregation DatabaseEuropeSub18482G=0.203A=0.796
The Genome Aggregation DatabaseGlobalStudy-wide29934G=0.383A=0.616
The Genome Aggregation DatabaseOtherSub300G=0.370A=0.630
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.485A=0.514
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.224A=0.776
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs71446494E-06alcohol consumption23743675

eQTL of rs7144649 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7144649 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr145786149457861544E06739278
chr145786006157860141E06837845
chr145786006157860141E07037845
chr145786006157860141E07137845
chr145786149457861544E07139278
chr145786600757866112E07243791
chr145786149457861544E08139278
chr145786006157860141E08237845







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr145785623457859075E06734018
chr145785915857859400E06736942
chr145785623457859075E06834018
chr145785915857859400E06836942
chr145785623457859075E06934018
chr145785915857859400E06936942
chr145785623457859075E07034018
chr145785915857859400E07036942
chr145785623457859075E07134018
chr145785915857859400E07136942
chr145785623457859075E07234018
chr145785915857859400E07236942
chr145785623457859075E07334018
chr145785915857859400E07336942
chr145785623457859075E07434018
chr145785915857859400E07436942
chr145785623457859075E08134018
chr145785915857859400E08136942
chr145785623457859075E08234018
chr145785915857859400E08236942