rs7148434

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0066 (1970/29590,GnomAD)
G=0091 (2650/29118,TOPMED)
G=0099 (494/5008,1000G)
G=0022 (83/3854,ALSPAC)
G=0024 (90/3708,TWINSUK)
chr14:95011422 (GRCh38.p7) (14q32.13)
AD
GWASdb2
1   publication(s)
See rs on genome
16 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.95011422A>G
GRCh37.p13 chr 14NC_000014.8:g.95477759A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.801G=0.199
1000GenomesAmericanSub694A=0.930G=0.070
1000GenomesEast AsianSub1008A=0.885G=0.115
1000GenomesEuropeSub1006A=0.973G=0.027
1000GenomesGlobalStudy-wide5008A=0.901G=0.099
1000GenomesSouth AsianSub978A=0.960G=0.040
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.978G=0.022
The Genome Aggregation DatabaseAfricanSub8664A=0.846G=0.154
The Genome Aggregation DatabaseAmericanSub798A=0.920G=0.080
The Genome Aggregation DatabaseEast AsianSub1616A=0.901G=0.099
The Genome Aggregation DatabaseEuropeSub18210A=0.978G=0.021
The Genome Aggregation DatabaseGlobalStudy-wide29590A=0.933G=0.066
The Genome Aggregation DatabaseOtherSub302A=0.940G=0.060
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.909G=0.091
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.976G=0.024
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs71484340.000915alcohol dependence21314694

eQTL of rs7148434 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7148434 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr149547734895477508E069-251
chr149547756295477683E069-76
chr149547856495478690E070805
chr149550120895501286E07023449
chr149550131695501394E07023557
chr149546765995467852E081-9907
chr149547219495472293E081-5466
chr149547247595472676E081-5083
chr149547278095472963E081-4796
chr149547690695477307E081-452
chr149547734895477508E081-251
chr149547756295477683E081-76
chr149547856495478690E081805
chr149545605295456102E082-21657
chr149545614995456257E082-21502
chr149547856495478690E082805