rs7148751

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0274 (8207/29910,GnomAD)
A=0287 (8373/29118,TOPMED)
A=0316 (1585/5008,1000G)
A=0232 (895/3854,ALSPAC)
A=0224 (829/3708,TWINSUK)
chr14:49402182 (GRCh38.p7) (14q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
23 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.49402182G>A
GRCh37.p13 chr 14NC_000014.8:g.49868900G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.616A=0.384
1000GenomesAmericanSub694G=0.670A=0.330
1000GenomesEast AsianSub1008G=0.627A=0.373
1000GenomesEuropeSub1006G=0.781A=0.219
1000GenomesGlobalStudy-wide5008G=0.684A=0.316
1000GenomesSouth AsianSub978G=0.740A=0.260
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.768A=0.232
The Genome Aggregation DatabaseAfricanSub8694G=0.646A=0.354
The Genome Aggregation DatabaseAmericanSub836G=0.640A=0.360
The Genome Aggregation DatabaseEast AsianSub1600G=0.561A=0.439
The Genome Aggregation DatabaseEuropeSub18480G=0.780A=0.219
The Genome Aggregation DatabaseGlobalStudy-wide29910G=0.725A=0.274
The Genome Aggregation DatabaseOtherSub300G=0.780A=0.220
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.712A=0.287
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.776A=0.224
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs71487510.000808alcohol dependence20201924

eQTL of rs7148751 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7148751 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144991418849914739E06745288
chr144991489849914978E06745998
chr144991395049914001E06945050
chr144991418849914739E06945288
chr144989388149894179E07024981
chr144991395049914001E07045050
chr144991418849914739E07045288
chr144991489849914978E07045998
chr144991507149915226E07046171
chr144991380749913847E07144907
chr144991395049914001E07145050
chr144991418849914739E07145288
chr144991380749913847E07244907
chr144991395049914001E07245050
chr144991418849914739E07245288
chr144991395049914001E07445050
chr144991418849914739E07445288
chr144991489849914978E07445998
chr144989388149894179E08124981
chr144990488549905587E08135985
chr144990564949905782E08136749
chr144991861449918675E08149714
chr144989317749893419E08224277