rs7149330

Homo sapiens
G>A
KCNK13 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0294 (8821/29926,GnomAD)
A=0344 (10037/29118,TOPMED)
A=0336 (1685/5008,1000G)
A=0157 (604/3854,ALSPAC)
A=0161 (597/3708,TWINSUK)
chr14:90169862 (GRCh38.p7) (14q32.11)
AD
GWASdb2
1   publication(s)
See rs on genome
1 Enhancer around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.90169862G>A
GRCh37.p13 chr 14NC_000014.8:g.90636206G>A

Gene: KCNK13, potassium two pore domain channel subfamily K member 13(plus strand)

Molecule type Change Amino acid[Codon] SO Term
KCNK13 transcriptNM_022054.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.353A=0.647
1000GenomesAmericanSub694G=0.830A=0.170
1000GenomesEast AsianSub1008G=0.776A=0.224
1000GenomesEuropeSub1006G=0.832A=0.168
1000GenomesGlobalStudy-wide5008G=0.664A=0.336
1000GenomesSouth AsianSub978G=0.670A=0.330
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.843A=0.157
The Genome Aggregation DatabaseAfricanSub8688G=0.413A=0.587
The Genome Aggregation DatabaseAmericanSub838G=0.870A=0.130
The Genome Aggregation DatabaseEast AsianSub1612G=0.779A=0.221
The Genome Aggregation DatabaseEuropeSub18486G=0.825A=0.174
The Genome Aggregation DatabaseGlobalStudy-wide29926G=0.705A=0.294
The Genome Aggregation DatabaseOtherSub302G=0.890A=0.110
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.655A=0.344
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.839A=0.161
PMID Title Author Journal
22096494A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study.Zuo LPLoS One

P-Value

SNP ID p-value Traits Study
rs71493308.5E-05alcohol dependence22096494

eQTL of rs7149330 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7149330 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr149064639190646586E06810185

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr149060996390610377E071-25829