rs7157217

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0168 (5046/29926,GnomAD)
T=0176 (5132/29118,TOPMED)
T=0155 (776/5008,1000G)
T=0127 (489/3854,ALSPAC)
T=0132 (491/3708,TWINSUK)
chr14:42438244 (GRCh38.p7) (14q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.42438244C>T
GRCh37.p13 chr 14NC_000014.8:g.42907447C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.700T=0.300
1000GenomesAmericanSub694C=0.930T=0.070
1000GenomesEast AsianSub1008C=0.885T=0.115
1000GenomesEuropeSub1006C=0.876T=0.124
1000GenomesGlobalStudy-wide5008C=0.845T=0.155
1000GenomesSouth AsianSub978C=0.910T=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.873T=0.127
The Genome Aggregation DatabaseAfricanSub8712C=0.723T=0.277
The Genome Aggregation DatabaseAmericanSub832C=0.920T=0.080
The Genome Aggregation DatabaseEast AsianSub1608C=0.934T=0.066
The Genome Aggregation DatabaseEuropeSub18472C=0.868T=0.131
The Genome Aggregation DatabaseGlobalStudy-wide29926C=0.831T=0.168
The Genome Aggregation DatabaseOtherSub302C=0.910T=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.823T=0.176
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.868T=0.132
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs71572170.00083alcohol dependence20201924

eQTL of rs7157217 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7157217 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.