rs7161221

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0196 (5884/29960,GnomAD)
C=0202 (5887/29118,TOPMED)
C=0119 (598/5008,1000G)
C=0256 (988/3854,ALSPAC)
C=0259 (962/3708,TWINSUK)
chr14:98426546 (GRCh38.p7) (14q32.2)
AD
GWASdb2
1   publication(s)
See rs on genome
12 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.98426546A>C
GRCh37.p13 chr 14NC_000014.8:g.98892883A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.875C=0.125
1000GenomesAmericanSub694A=0.870C=0.130
1000GenomesEast AsianSub1008A=0.996C=0.004
1000GenomesEuropeSub1006A=0.767C=0.233
1000GenomesGlobalStudy-wide5008A=0.881C=0.119
1000GenomesSouth AsianSub978A=0.890C=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.744C=0.256
The Genome Aggregation DatabaseAfricanSub8726A=0.850C=0.150
The Genome Aggregation DatabaseAmericanSub838A=0.870C=0.130
The Genome Aggregation DatabaseEast AsianSub1616A=0.996C=0.004
The Genome Aggregation DatabaseEuropeSub18478A=0.761C=0.238
The Genome Aggregation DatabaseGlobalStudy-wide29960A=0.803C=0.196
The Genome Aggregation DatabaseOtherSub302A=0.850C=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.797C=0.202
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.741C=0.259
PMID Title Author Journal
22072270Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.Wang KSJ Neural Transm (Vienna)

P-Value

SNP ID p-value Traits Study
rs71612212.86E-05alcohol withdrawal symptoms22072270

eQTL of rs7161221 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7161221 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr149887449998874599E068-18284
chr149887466698874727E068-18156
chr149887132498871714E070-21169
chr149887176298871822E070-21061
chr149893293698933033E07040053
chr149893318498933523E07040301
chr149893355498933779E07040671
chr149887388998873939E071-18944
chr149887449998874599E071-18284
chr149887466698874727E071-18156
chr149887449998874599E074-18284
chr149887466698874727E074-18156