rs7163369

Homo sapiens
G>A
SLCO3A1 : Intron Variant
LOC107984747 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0232 (6920/29778,GnomAD)
G==0209 (6106/29118,TOPMED)
G==0157 (785/5008,1000G)
G==0337 (1299/3854,ALSPAC)
G==0328 (1216/3708,TWINSUK)
chr15:91990684 (GRCh38.p7) (15q26.1)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.91990684G>A
GRCh37.p13 chr 15NC_000015.9:g.92533914G>A

Gene: SLCO3A1, solute carrier organic anion transporter family member 3A1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SLCO3A1 transcript variant 2NM_001145044.1:c.N/AIntron Variant
SLCO3A1 transcript variant 1NM_013272.3:c.N/AIntron Variant
SLCO3A1 transcript variant 3NR_135775.1:n.N/AIntron Variant
SLCO3A1 transcript variant X1XM_005254889.1:c.N/AIntron Variant
SLCO3A1 transcript variant X3XM_005254891.2:c.N/AIntron Variant
SLCO3A1 transcript variant X2XM_011521456.2:c.N/AIntron Variant
SLCO3A1 transcript variant X4XR_931795.1:n.N/AIntron Variant
SLCO3A1 transcript variant X5XR_931796.2:n.N/AIntron Variant

Gene: LOC107984747, uncharacterized LOC107984747(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107984747 transcriptXR_001751660.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.051A=0.949
1000GenomesAmericanSub694G=0.220A=0.780
1000GenomesEast AsianSub1008G=0.035A=0.965
1000GenomesEuropeSub1006G=0.341A=0.659
1000GenomesGlobalStudy-wide5008G=0.157A=0.843
1000GenomesSouth AsianSub978G=0.190A=0.810
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.337A=0.663
The Genome Aggregation DatabaseAfricanSub8694G=0.096A=0.904
The Genome Aggregation DatabaseAmericanSub838G=0.180A=0.820
The Genome Aggregation DatabaseEast AsianSub1622G=0.035A=0.965
The Genome Aggregation DatabaseEuropeSub18322G=0.316A=0.684
The Genome Aggregation DatabaseGlobalStudy-wide29778G=0.232A=0.767
The Genome Aggregation DatabaseOtherSub302G=0.290A=0.710
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.209A=0.790
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.328A=0.672
PMID Title Author Journal
22377092ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies.Wang KSDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs71633693.27E-06nicotine dependence (smoking)22377092

eQTL of rs7163369 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7163369 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr159248506592485408E067-48506
chr159248556792486785E067-47129
chr159248686792487170E067-46744
chr159248734692487404E067-46510
chr159248742692487529E067-46385
chr159248753692487630E067-46284
chr159248768592487821E067-46093
chr159248787792487917E067-45997
chr159248791892488077E067-45837
chr159248917492489224E067-44690
chr159248928992489426E067-44488
chr159248946492489565E067-44349
chr159248957592489665E067-44249
chr159248967692489732E067-44182
chr159248974892489854E067-44060
chr159249014692492222E067-41692
chr159249229392492455E067-41459
chr159249559192495831E067-38083
chr159249588892496110E067-37804
chr159249614392496383E067-37531
chr159249647192497199E067-36715
chr159249733092497520E067-36394
chr159249753992497883E067-36031
chr159250594792505997E067-27917
chr159250819092508290E067-25624
chr159250858392509865E067-24049
chr159250993392510212E067-23702
chr159251029192510335E067-23579
chr159251058092510630E067-23284
chr159251097792511406E067-22508
chr159251149792511724E067-22190
chr159251185392512133E067-21781
chr159251215892512232E067-21682
chr159251230992512359E067-21555
chr159251291792512962E067-20952
chr159251303492513086E067-20828
chr159251317992514068E067-19846
chr159251652292516604E067-17310
chr159251684592516976E067-16938
chr159251703692517118E067-16796
chr159251731992517392E067-16522
chr159251743092517474E067-16440
chr159251762792517872E067-16042
chr159251799792518050E067-15864
chr159251856692518776E067-15138
chr159251879192519179E067-14735
chr159252901192529068E067-4846
chr159252912192529223E067-4691
chr159253222892532278E067-1636
chr159253229892532439E067-1475
chr159253406192534276E067147
chr159253468592534762E067771
chr159253568292535749E0671768
chr159253580792535875E0671893
chr159253595292536078E0672038
chr159254390092543957E0679986
chr159254400792544394E06710093
chr159254448192544556E06710567
chr159254466892544883E06710754
chr159254493092545052E06711016
chr159254510492545336E06711190
chr159254681692546970E06712902
chr159254710192547229E06713187
chr159254728492547359E06713370
chr159254746392547572E06713549
chr159254767092547720E06713756
chr159254939592549456E06715481
chr159254951992549859E06715605
chr159255004392550103E06716129
chr159255026792550307E06716353
chr159255184292552026E06717928
chr159255205392552142E06718139
chr159255235692552456E06718442
chr159255248792552640E06718573
chr159255266592552753E06718751
chr159255281892552868E06718904
chr159255294292552992E06719028
chr159255318492553298E06719270
chr159255419692554264E06720282
chr159255430792554357E06720393
chr159255454692554639E06720632
chr159255476092555808E06720846
chr159255585692555936E06721942
chr159255613092556193E06722216
chr159255624692556290E06722332
chr159255636192556449E06722447
chr159255647392556523E06722559
chr159255653892556609E06722624
chr159255661492556720E06722700
chr159255698392557033E06723069
chr159255735092557400E06723436
chr159255744392557568E06723529
chr159255762392557828E06723709
chr159255787192557921E06723957
chr159255799192558157E06724077
chr159255888292558941E06724968
chr159255897592559025E06725061
chr159256066092561866E06726746
chr159256502692565076E06731112
chr159256512292565223E06731208
chr159256523692565297E06731322
chr159256543292565485E06731518
chr159256553492565584E06731620
chr159256578692565846E06731872
chr159256591592565971E06732001
chr159257070492570847E06736790
chr159257087392570961E06736959
chr159257112692571253E06737212
chr159257129292571342E06737378
chr159257137492572807E06737460
chr159257297992573495E06739065
chr159257357592573700E06739661
chr159257402292574503E06740108
chr159257456892574700E06740654
chr159257478292574851E06740868
chr159257594792576010E06742033
chr159257649092577126E06742576
chr159257715992577234E06743245
chr159257728392577333E06743369
chr159257894992579035E06745035
chr159257914392579337E06745229
chr159257935792579569E06745443
chr159248506592485408E068-48506
chr159248556792486785E068-47129
chr159248686792487170E068-46744
chr159248734692487404E068-46510
chr159248742692487529E068-46385
chr159248753692487630E068-46284
chr159248768592487821E068-46093
chr159248787792487917E068-45997
chr159248791892488077E068-45837
chr159248883692488950E068-44964
chr159248917492489224E068-44690
chr159248928992489426E068-44488
chr159248946492489565E068-44349
chr159248957592489665E068-44249
chr159248967692489732E068-44182
chr159248974892489854E068-44060
chr159248987392490079E068-43835
chr159249014692492222E068-41692
chr159249922492500003E068-33911
chr159250819092508290E068-25624
chr159250858392509865E068-24049
chr159250993392510212E068-23702
chr159251029192510335E068-23579
chr159251058092510630E068-23284
chr159251097792511406E068-22508
chr159251149792511724E068-22190
chr159251185392512133E068-21781
chr159251215892512232E068-21682
chr159251230992512359E068-21555
chr159251291792512962E068-20952
chr159251303492513086E068-20828
chr159251317992514068E068-19846
chr159251410192514163E068-19751
chr159251417392514307E068-19607
chr159251452992514579E068-19335
chr159251473292514800E068-19114
chr159251480392514853E068-19061
chr159251500392515096E068-18818
chr159251684592516976E068-16938
chr159251703692517118E068-16796
chr159251731992517392E068-16522
chr159251743092517474E068-16440
chr159251762792517872E068-16042
chr159251799792518050E068-15864
chr159251856692518776E068-15138
chr159251879192519179E068-14735
chr159252251492522653E068-11261
chr159252269492522744E068-11170
chr159252278892522902E068-11012
chr159252295292523125E068-10789
chr159252317692523590E068-10324
chr159252834392528454E068-5460
chr159252880292528852E068-5062
chr159252887592528982E068-4932
chr159253352992533688E068-226
chr159253373492533860E068-54
chr159253406192534276E068147
chr159254666592546778E06812751
chr159254681692546970E06812902
chr159254710192547229E06813187
chr159254728492547359E06813370
chr159254746392547572E06813549
chr159254767092547720E06813756
chr159254782392547871E06813909
chr159254847292548851E06814558
chr159254897492549028E06815060
chr159254908392549253E06815169
chr159254939592549456E06815481
chr159254951992549859E06815605
chr159255004392550103E06816129
chr159255026792550307E06816353
chr159255062992550716E06816715
chr159255235692552456E06818442
chr159255248792552640E06818573
chr159255266592552753E06818751
chr159255281892552868E06818904
chr159255294292552992E06819028
chr159255318492553298E06819270
chr159255357092553645E06819656
chr159255419692554264E06820282
chr159255430792554357E06820393
chr159255454692554639E06820632
chr159255476092555808E06820846
chr159255585692555936E06821942
chr159255613092556193E06822216
chr159255624692556290E06822332
chr159255636192556449E06822447
chr159255647392556523E06822559
chr159255653892556609E06822624
chr159255661492556720E06822700
chr159255698392557033E06823069
chr159255735092557400E06823436
chr159255744392557568E06823529
chr159255762392557828E06823709
chr159255787192557921E06823957
chr159255799192558157E06824077
chr159256212292562524E06828208
chr159256502692565076E06831112
chr159256512292565223E06831208
chr159256523692565297E06831322
chr159256722792567435E06833313
chr159256743892567521E06833524
chr159256766492567708E06833750
chr159256860592568880E06834691
chr159256899292569271E06835078
chr159256946492569514E06835550
chr159256954692569586E06835632
chr159257649092577126E06842576
chr159257715992577234E06843245
chr159257728392577333E06843369
chr159248482492484904E069-49010
chr159248506592485408E069-48506
chr159248556792486785E069-47129
chr159248686792487170E069-46744
chr159248734692487404E069-46510
chr159248742692487529E069-46385
chr159248753692487630E069-46284
chr159248768592487821E069-46093
chr159248787792487917E069-45997
chr159248791892488077E069-45837
chr159248917492489224E069-44690
chr159248928992489426E069-44488
chr159248946492489565E069-44349
chr159248957592489665E069-44249
chr159248967692489732E069-44182
chr159248974892489854E069-44060
chr159248987392490079E069-43835
chr159249014692492222E069-41692
chr159249229392492455E069-41459
chr159249330292493713E069-40201
chr159249647192497199E069-36715
chr159249794192498026E069-35888
chr159249814592498252E069-35662
chr159249834492498394E069-35520
chr159249841792498508E069-35406
chr159249909192499223E069-34691
chr159250574692505822E069-28092
chr159250594792505997E069-27917
chr159250603692506123E069-27791
chr159250819092508290E069-25624
chr159250858392509865E069-24049
chr159250993392510212E069-23702
chr159251029192510335E069-23579
chr159251058092510630E069-23284
chr159251097792511406E069-22508
chr159251149792511724E069-22190
chr159251185392512133E069-21781
chr159251215892512232E069-21682
chr159251230992512359E069-21555
chr159251291792512962E069-20952
chr159251303492513086E069-20828
chr159251317992514068E069-19846
chr159251410192514163E069-19751
chr159251417392514307E069-19607
chr159251452992514579E069-19335
chr159251473292514800E069-19114
chr159251480392514853E069-19061
chr159251641392516486E069-17428
chr159251652292516604E069-17310
chr159251684592516976E069-16938
chr159251703692517118E069-16796
chr159251731992517392E069-16522
chr159251743092517474E069-16440
chr159251762792517872E069-16042
chr159251799792518050E069-15864
chr159251856692518776E069-15138
chr159251879192519179E069-14735
chr159252317692523590E069-10324
chr159252422292524371E069-9543
chr159252834392528454E069-5460
chr159252851092528560E069-5354
chr159252880292528852E069-5062
chr159252887592528982E069-4932
chr159253332192533401E069-513
chr159253352992533688E069-226
chr159253373492533860E069-54
chr159253406192534276E069147
chr159253540092535450E0691486
chr159253568292535749E0691768
chr159253580792535875E0691893
chr159253595292536078E0692038
chr159253609092536208E0692176
chr159253625592536543E0692341
chr159253662592536706E0692711
chr159253802792538106E0694113
chr159253866492538704E0694750
chr159254390092543957E0699986
chr159254400792544394E06910093
chr159254466892544883E06910754
chr159254641892546483E06912504
chr159254652692546596E06912612
chr159254666592546778E06912751
chr159254681692546970E06912902
chr159254710192547229E06913187
chr159254728492547359E06913370
chr159254746392547572E06913549
chr159254767092547720E06913756
chr159254782392547871E06913909
chr159254908392549253E06915169
chr159254939592549456E06915481
chr159254951992549859E06915605
chr159255004392550103E06916129
chr159255026792550307E06916353
chr159255062992550716E06916715
chr159255281892552868E06918904
chr159255294292552992E06919028
chr159255318492553298E06919270
chr159255357092553645E06919656
chr159255419692554264E06920282
chr159255430792554357E06920393
chr159255454692554639E06920632
chr159255476092555808E06920846
chr159255585692555936E06921942
chr159255613092556193E06922216
chr159255624692556290E06922332
chr159255636192556449E06922447
chr159255647392556523E06922559
chr159255653892556609E06922624
chr159255661492556720E06922700
chr159255698392557033E06923069
chr159255735092557400E06923436
chr159255744392557568E06923529
chr159255762392557828E06923709
chr159255787192557921E06923957
chr159255799192558157E06924077
chr159255888292558941E06924968
chr159255897592559025E06925061
chr159255968892559766E06925774
chr159255990392559953E06925989
chr159256033292560400E06926418
chr159256066092561866E06926746
chr159256212292562524E06928208
chr159256282392562888E06928909
chr159256293292562996E06929018
chr159256311392563165E06929199
chr159256317292563257E06929258
chr159256722792567435E06933313
chr159256743892567521E06933524
chr159256766492567708E06933750
chr159256812792568224E06934213
chr159256840492568452E06934490
chr159256860592568880E06934691
chr159256899292569271E06935078
chr159256946492569514E06935550
chr159256954692569586E06935632
chr159257297992573495E06939065
chr159257357592573700E06939661
chr159257402292574503E06940108
chr159257456892574700E06940654
chr159257478292574851E06940868
chr159257511392575157E06941199
chr159257524292575284E06941328
chr159257552592575575E06941611
chr159257594792576010E06942033
chr159257649092577126E06942576
chr159257715992577234E06943245
chr159257728392577333E06943369
chr159257761392577718E06943699
chr159257894992579035E06945035
chr159257914392579337E06945229
chr159257935792579569E06945443
chr159254400792544394E07010093
chr159254448192544556E07010567
chr159254466892544883E07010754
chr159254493092545052E07011016
chr159248482492484904E071-49010
chr159248506592485408E071-48506
chr159248556792486785E071-47129
chr159248686792487170E071-46744
chr159248734692487404E071-46510
chr159248742692487529E071-46385
chr159248753692487630E071-46284
chr159248768592487821E071-46093
chr159248787792487917E071-45997
chr159248791892488077E071-45837
chr159248917492489224E071-44690
chr159248928992489426E071-44488
chr159248946492489565E071-44349
chr159248957592489665E071-44249
chr159248967692489732E071-44182
chr159248974892489854E071-44060
chr159248987392490079E071-43835
chr159249014692492222E071-41692
chr159249229392492455E071-41459
chr159249272892492809E071-41105
chr159249287292492922E071-40992
chr159249295092492990E071-40924
chr159249330292493713E071-40201
chr159249380892494561E071-39353
chr159249457492494728E071-39186
chr159249513492495203E071-38711
chr159249559192495831E071-38083
chr159249588892496110E071-37804
chr159249614392496383E071-37531
chr159249647192497199E071-36715
chr159249733092497520E071-36394
chr159249753992497883E071-36031
chr159249794192498026E071-35888
chr159249814592498252E071-35662
chr159249834492498394E071-35520
chr159249841792498508E071-35406
chr159249896992499036E071-34878
chr159249909192499223E071-34691
chr159250453092504879E071-29035
chr159250492892504982E071-28932
chr159250501292505088E071-28826
chr159250574692505822E071-28092
chr159250594792505997E071-27917
chr159250603692506123E071-27791
chr159250742492507474E071-26440
chr159250751192507585E071-26329
chr159250763492507689E071-26225
chr159250819092508290E071-25624
chr159250858392509865E071-24049
chr159250993392510212E071-23702
chr159251029192510335E071-23579
chr159251058092510630E071-23284
chr159251097792511406E071-22508
chr159251149792511724E071-22190
chr159251185392512133E071-21781
chr159251215892512232E071-21682
chr159251230992512359E071-21555
chr159251291792512962E071-20952
chr159251303492513086E071-20828
chr159251317992514068E071-19846
chr159251410192514163E071-19751
chr159251417392514307E071-19607
chr159251452992514579E071-19335
chr159251473292514800E071-19114
chr159251480392514853E071-19061
chr159251500392515096E071-18818
chr159251553092515610E071-18304
chr159251568692515730E071-18184
chr159251641392516486E071-17428
chr159251652292516604E071-17310
chr159251684592516976E071-16938
chr159251703692517118E071-16796
chr159251731992517392E071-16522
chr159251743092517474E071-16440
chr159251762792517872E071-16042
chr159251799792518050E071-15864
chr159251856692518776E071-15138
chr159251879192519179E071-14735
chr159252278892522902E071-11012
chr159252295292523125E071-10789
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chr159256812792568224E08134213
chr159256840492568452E08134490
chr159257112692571253E08137212
chr159257129292571342E08137378
chr159257137492572807E08137460
chr159257649092577126E08142576
chr159257715992577234E08143245
chr159257728392577333E08143369
chr159257761392577718E08143699
chr159248556792486785E082-47129
chr159249014692492222E082-41692
chr159254400792544394E08210093
chr159254448192544556E08210567
chr159254466892544883E08210754
chr159255430792554357E08220393
chr159255476092555808E08220846