rs7172677

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
A==0304 (9100/29928,GnomAD)
A==0283 (8256/29118,TOPMED)
A==0265 (1325/5008,1000G)
A==0258 (993/3854,ALSPAC)
A==0261 (968/3708,TWINSUK)
chr15:75132252 (GRCh38.p7) (15q24.2)
AD
GWASdb2
1   publication(s)
See rs on genome
28 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.75132252A>C
GRCh37.p13 chr 15NC_000015.9:g.75424593A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.293C=0.707
1000GenomesAmericanSub694A=0.250C=0.750
1000GenomesEast AsianSub1008A=0.201C=0.799
1000GenomesEuropeSub1006A=0.301C=0.699
1000GenomesGlobalStudy-wide5008A=0.265C=0.735
1000GenomesSouth AsianSub978A=0.270C=0.730
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.258C=0.742
The Genome Aggregation DatabaseAfricanSub8706A=0.313C=0.687
The Genome Aggregation DatabaseAmericanSub832A=0.310C=0.690
The Genome Aggregation DatabaseEast AsianSub1618A=0.240C=0.760
The Genome Aggregation DatabaseEuropeSub18470A=0.306C=0.693
The Genome Aggregation DatabaseGlobalStudy-wide29928A=0.304C=0.695
The Genome Aggregation DatabaseOtherSub302A=0.230C=0.770
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.283C=0.716
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.261C=0.739
PMID Title Author Journal
23089632A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.Wang JCMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs71726770.00000715alcohol dependence23089632
rs71726770.000535alcohol dependence23089632

eQTL of rs7172677 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7172677 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr157546992175472422E06745328
chr157547254975473559E06747956
chr157538201175382398E068-42195
chr157540728775407428E068-17165
chr157546992175472422E06845328
chr157547254975473559E06847956
chr157540728775407428E069-17165
chr157546992175472422E06945328
chr157547254975473559E06947956
chr157547254975473559E07047956
chr157539698875397911E071-26682
chr157540253175402680E071-21913
chr157541656375416758E071-7835
chr157547254975473559E07147956
chr157547425775474404E07149664
chr157546992175472422E07245328
chr157540728775407428E073-17165
chr157546977075469901E07345177
chr157546992175472422E07345328
chr157547425775474404E07349664
chr157540728775407428E074-17165
chr157546992175472422E07445328
chr157547254975473559E07447956
chr157547425775474404E07449664
chr157546992175472422E08145328
chr157547254975473559E08147956
chr157546992175472422E08245328
chr157547254975473559E08247956