rs7173864

Homo sapiens
T>C
SLCO3A1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0118 (3534/29916,GnomAD)
C=0122 (3571/29118,TOPMED)
C=0168 (843/5008,1000G)
C=0102 (393/3854,ALSPAC)
C=0098 (364/3708,TWINSUK)
chr15:92067237 (GRCh38.p7) (15q26.1)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.92067237T>C
GRCh37.p13 chr 15NC_000015.9:g.92610467T>C

Gene: SLCO3A1, solute carrier organic anion transporter family member 3A1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SLCO3A1 transcript variant 2NM_001145044.1:c.N/AIntron Variant
SLCO3A1 transcript variant 1NM_013272.3:c.N/AIntron Variant
SLCO3A1 transcript variant 3NR_135775.1:n.N/AIntron Variant
SLCO3A1 transcript variant X1XM_005254889.1:c.N/AIntron Variant
SLCO3A1 transcript variant X3XM_005254891.2:c.N/AIntron Variant
SLCO3A1 transcript variant X2XM_011521456.2:c.N/AIntron Variant
SLCO3A1 transcript variant X4XR_931795.1:n.N/AIntron Variant
SLCO3A1 transcript variant X5XR_931796.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.853C=0.147
1000GenomesAmericanSub694T=0.910C=0.090
1000GenomesEast AsianSub1008T=0.754C=0.246
1000GenomesEuropeSub1006T=0.917C=0.083
1000GenomesGlobalStudy-wide5008T=0.832C=0.168
1000GenomesSouth AsianSub978T=0.740C=0.260
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.898C=0.102
The Genome Aggregation DatabaseAfricanSub8706T=0.855C=0.145
The Genome Aggregation DatabaseAmericanSub836T=0.930C=0.070
The Genome Aggregation DatabaseEast AsianSub1614T=0.734C=0.266
The Genome Aggregation DatabaseEuropeSub18458T=0.904C=0.095
The Genome Aggregation DatabaseGlobalStudy-wide29916T=0.881C=0.118
The Genome Aggregation DatabaseOtherSub302T=0.930C=0.070
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.877C=0.122
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.902C=0.098
PMID Title Author Journal
22377092ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies.Wang KSDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs71738649.23E-05nicotine dependence (smoking)22377092

eQTL of rs7173864 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7173864 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr159256066092561866E067-48601
chr159256502692565076E067-45391
chr159256512292565223E067-45244
chr159256523692565297E067-45170
chr159256543292565485E067-44982
chr159256553492565584E067-44883
chr159256578692565846E067-44621
chr159256591592565971E067-44496
chr159257070492570847E067-39620
chr159257087392570961E067-39506
chr159257112692571253E067-39214
chr159257129292571342E067-39125
chr159257137492572807E067-37660
chr159257297992573495E067-36972
chr159257357592573700E067-36767
chr159257402292574503E067-35964
chr159257456892574700E067-35767
chr159257478292574851E067-35616
chr159257594792576010E067-34457
chr159257649092577126E067-33341
chr159257715992577234E067-33233
chr159257728392577333E067-33134
chr159257894992579035E067-31432
chr159257914392579337E067-31130
chr159257935792579569E067-30898
chr159258442592584475E067-25992
chr159258530192585518E067-24949
chr159258571192585761E067-24706
chr159258577692585833E067-24634
chr159259094092591142E067-19325
chr159259123292591393E067-19074
chr159259265892592745E067-17722
chr159259290292593127E067-17340
chr159259321192593357E067-17110
chr159259340792593470E067-16997
chr159259349692593825E067-16642
chr159259389592594090E067-16377
chr159259488092594979E067-15488
chr159259501392595226E067-15241
chr159259527892595351E067-15116
chr159259702192597140E067-13327
chr159259732992597447E067-13020
chr159260021092600439E067-10028
chr159260130592601360E067-9107
chr159260136392601489E067-8978
chr159260175392601852E067-8615
chr159260203192602145E067-8322
chr159260218192602891E067-7576
chr159260296092603489E067-6978
chr159260439192604542E067-5925
chr159260465792604759E067-5708
chr159260496192605052E067-5415
chr159260513292605252E067-5215
chr159261006892610118E067-349
chr159261017192610221E067-246
chr159261065292610768E067185
chr159261084692611026E067379
chr159261143392611742E067966
chr159261175892611831E0671291
chr159261230392612369E0671836
chr159261239892612629E0671931
chr159261271692613464E0672249
chr159261347192613853E0673004
chr159261434292614723E0673875
chr159261474292614971E0674275
chr159261499892615141E0674531
chr159261514792615355E0674680
chr159261765892618341E0677191
chr159261959492619674E0679127
chr159261974992619799E0679282
chr159261990192620042E0679434
chr159262048192620992E06710014
chr159262106492621155E06710597
chr159262510792625212E06714640
chr159262522192626027E06714754
chr159263353392633583E06723066
chr159263361192633651E06723144
chr159263365592633750E06723188
chr159263378292633832E06723315
chr159263431792634707E06723850
chr159263473792634942E06724270
chr159263497592635025E06724508
chr159264057292641568E06730105
chr159264160592641655E06731138
chr159264169692641752E06731229
chr159264187492642645E06731407
chr159264272392642773E06732256
chr159264284892642937E06732381
chr159264528892645931E06734821
chr159265410592654290E06743638
chr159265437792655334E06743910
chr159265537992656091E06744912
chr159265994892660127E06749481
chr159266024792660324E06749780
chr159256212292562524E068-47943
chr159256502692565076E068-45391
chr159256512292565223E068-45244
chr159256523692565297E068-45170
chr159256722792567435E068-43032
chr159256743892567521E068-42946
chr159256766492567708E068-42759
chr159256860592568880E068-41587
chr159256899292569271E068-41196
chr159256946492569514E068-40953
chr159256954692569586E068-40881
chr159257649092577126E068-33341
chr159257715992577234E068-33233
chr159257728392577333E068-33134
chr159258442592584475E068-25992
chr159258514892585198E068-25269
chr159258530192585518E068-24949
chr159258571192585761E068-24706
chr159258577692585833E068-24634
chr159259265892592745E068-17722
chr159259290292593127E068-17340
chr159259321192593357E068-17110
chr159259340792593470E068-16997
chr159259349692593825E068-16642
chr159259389592594090E068-16377
chr159259450792594581E068-15886
chr159259702192597140E068-13327
chr159259732992597447E068-13020
chr159260439192604542E068-5925
chr159260465792604759E068-5708
chr159260496192605052E068-5415
chr159260513292605252E068-5215
chr159260540392606212E068-4255
chr159261143392611742E068966
chr159261175892611831E0681291
chr159261230392612369E0681836
chr159261239892612629E0681931
chr159261271692613464E0682249
chr159261347192613853E0683004
chr159261434292614723E0683875
chr159261474292614971E0684275
chr159261499892615141E0684531
chr159261514792615355E0684680
chr159261636292616751E0685895
chr159261677592616865E0686308
chr159261691892617000E0686451
chr159262289192623116E06812424
chr159262319192623241E06812724
chr159262334492623404E06812877
chr159262510792625212E06814640
chr159262522192626027E06814754
chr159263361192633651E06823144
chr159263365592633750E06823188
chr159263378292633832E06823315
chr159263431792634707E06823850
chr159263473792634942E06824270
chr159263497592635025E06824508
chr159263502792635138E06824560
chr159263517592635237E06824708
chr159264057292641568E06830105
chr159264160592641655E06831138
chr159264169692641752E06831229
chr159264177292641825E06831305
chr159264187492642645E06831407
chr159264272392642773E06832256
chr159264284892642937E06832381
chr159264528892645931E06834821
chr159265270392653499E06842236
chr159265351092653573E06843043
chr159265410592654290E06843638
chr159265437792655334E06843910
chr159265537992656091E06844912
chr159265629292656373E06845825
chr159265673892656788E06846271
chr159265958992659847E06849122
chr159265994892660127E06849481
chr159266024792660324E06849780
chr159256066092561866E069-48601
chr159256212292562524E069-47943
chr159256282392562888E069-47579
chr159256293292562996E069-47471
chr159256311392563165E069-47302
chr159256317292563257E069-47210
chr159256722792567435E069-43032
chr159256743892567521E069-42946
chr159256766492567708E069-42759
chr159256812792568224E069-42243
chr159256840492568452E069-42015
chr159256860592568880E069-41587
chr159256899292569271E069-41196
chr159256946492569514E069-40953
chr159256954692569586E069-40881
chr159257297992573495E069-36972
chr159257357592573700E069-36767
chr159257402292574503E069-35964
chr159257456892574700E069-35767
chr159257478292574851E069-35616
chr159257511392575157E069-35310
chr159257524292575284E069-35183
chr159257552592575575E069-34892
chr159257594792576010E069-34457
chr159257649092577126E069-33341
chr159257715992577234E069-33233
chr159257728392577333E069-33134
chr159257761392577718E069-32749
chr159257894992579035E069-31432
chr159257914392579337E069-31130
chr159257935792579569E069-30898
chr159258471392584962E069-25505
chr159258514892585198E069-25269
chr159258530192585518E069-24949
chr159258571192585761E069-24706
chr159258577692585833E069-24634
chr159258603992586096E069-24371
chr159259123292591393E069-19074
chr159259140092591470E069-18997
chr159259149692591550E069-18917
chr159259163792591752E069-18715
chr159259211392592334E069-18133
chr159259245592592505E069-17962
chr159259265892592745E069-17722
chr159259290292593127E069-17340
chr159259321192593357E069-17110
chr159259340792593470E069-16997
chr159259349692593825E069-16642
chr159259389592594090E069-16377
chr159259450792594581E069-15886
chr159259488092594979E069-15488
chr159259501392595226E069-15241
chr159259527892595351E069-15116
chr159259702192597140E069-13327
chr159259732992597447E069-13020
chr159259932592599438E069-11029
chr159259948492599547E069-10920
chr159260021092600439E069-10028
chr159260130592601360E069-9107
chr159260136392601489E069-8978
chr159260175392601852E069-8615
chr159260203192602145E069-8322
chr159260218192602891E069-7576
chr159260423792604301E069-6166
chr159260439192604542E069-5925
chr159260465792604759E069-5708
chr159260496192605052E069-5415
chr159260513292605252E069-5215
chr159260540392606212E069-4255
chr159260977792609824E069-643
chr159261006892610118E069-349
chr159261017192610221E069-246
chr159261065292610768E069185
chr159261084692611026E069379
chr159261143392611742E069966
chr159261175892611831E0691291
chr159261230392612369E0691836
chr159261239892612629E0691931
chr159261271692613464E0692249
chr159261347192613853E0693004
chr159261434292614723E0693875
chr159261474292614971E0694275
chr159261499892615141E0694531
chr159261514792615355E0694680
chr159261587592615925E0695408
chr159261702192617077E0696554
chr159261734092617413E0696873
chr159261746992617657E0697002
chr159261765892618341E0697191
chr159261838592618533E0697918
chr159261857792618657E0698110
chr159261877192618871E0698304
chr159261893792619443E0698470
chr159261959492619674E0699127
chr159261974992619799E0699282
chr159261990192620042E0699434
chr159262019892620307E0699731
chr159262032992620454E0699862
chr159262048192620992E06910014
chr159262106492621155E06910597
chr159262289192623116E06912424
chr159262319192623241E06912724
chr159262334492623404E06912877
chr159262383592623941E06913368
chr159262399692624046E06913529
chr159262510792625212E06914640
chr159262522192626027E06914754
chr159263317192633232E06922704
chr159263330892633393E06922841
chr159263353392633583E06923066
chr159263361192633651E06923144
chr159263365592633750E06923188
chr159263378292633832E06923315
chr159263473792634942E06924270
chr159263497592635025E06924508
chr159263502792635138E06924560
chr159263517592635237E06924708
chr159263647292636711E06926005
chr159264057292641568E06930105
chr159264160592641655E06931138
chr159264169692641752E06931229
chr159264177292641825E06931305
chr159264497092645260E06934503
chr159264528892645931E06934821
chr159264636092646454E06935893
chr159264657792646654E06936110
chr159264680992646863E06936342
chr159265242792652661E06941960
chr159265270392653499E06942236
chr159265351092653573E06943043
chr159265410592654290E06943638
chr159265437792655334E06943910
chr159265537992656091E06944912
chr159265629292656373E06945825
chr159265673892656788E06946271
chr159265923492659355E06948767
chr159265958992659847E06949122
chr159265994892660127E06949481
chr159266024792660324E06949780
chr159262510792625212E07014640
chr159262522192626027E07014754
chr159264057292641568E07030105
chr159264702492647078E07036557
chr159264718592647416E07036718
chr159256066092561866E071-48601
chr159256212292562524E071-47943
chr159256282392562888E071-47579
chr159256293292562996E071-47471
chr159256311392563165E071-47302
chr159256317292563257E071-47210
chr159256502692565076E071-45391
chr159256512292565223E071-45244
chr159256523692565297E071-45170
chr159256543292565485E071-44982
chr159256553492565584E071-44883
chr159256578692565846E071-44621
chr159256591592565971E071-44496
chr159256621092566270E071-44197
chr159256705992567109E071-43358
chr159256722792567435E071-43032
chr159256743892567521E071-42946
chr159256766492567708E071-42759
chr159256812792568224E071-42243
chr159256840492568452E071-42015
chr159256860592568880E071-41587
chr159256899292569271E071-41196
chr159256946492569514E071-40953
chr159256954692569586E071-40881
chr159257112692571253E071-39214
chr159257129292571342E071-39125
chr159257137492572807E071-37660
chr159257283492572895E071-37572
chr159257297992573495E071-36972
chr159257357592573700E071-36767
chr159257402292574503E071-35964
chr159257456892574700E071-35767
chr159257478292574851E071-35616
chr159257511392575157E071-35310
chr159257524292575284E071-35183
chr159257552592575575E071-34892
chr159257594792576010E071-34457
chr159257649092577126E071-33341
chr159257715992577234E071-33233
chr159257728392577333E071-33134
chr159257761392577718E071-32749
chr159258471392584962E071-25505
chr159258514892585198E071-25269
chr159258530192585518E071-24949
chr159259140092591470E071-18997
chr159259149692591550E071-18917
chr159259163792591752E071-18715
chr159259211392592334E071-18133
chr159259245592592505E071-17962
chr159259265892592745E071-17722
chr159259290292593127E071-17340
chr159259321192593357E071-17110
chr159259340792593470E071-16997
chr159259349692593825E071-16642
chr159259389592594090E071-16377
chr159259450792594581E071-15886
chr159259488092594979E071-15488
chr159259501392595226E071-15241
chr159259527892595351E071-15116
chr159259732992597447E071-13020
chr159259770592597791E071-12676
chr159259932592599438E071-11029
chr159259948492599547E071-10920
chr159260021092600439E071-10028
chr159260130592601360E071-9107
chr159260136392601489E071-8978
chr159260175392601852E071-8615
chr159260203192602145E071-8322
chr159260218192602891E071-7576
chr159260296092603489E071-6978
chr159260439192604542E071-5925
chr159260465792604759E071-5708
chr159260496192605052E071-5415
chr159260513292605252E071-5215
chr159260540392606212E071-4255
chr159261065292610768E071185
chr159261084692611026E071379
chr159261143392611742E071966
chr159261175892611831E0711291
chr159261230392612369E0711836
chr159261239892612629E0711931
chr159261271692613464E0712249
chr159261347192613853E0713004
chr159261434292614723E0713875
chr159261474292614971E0714275
chr159261499892615141E0714531
chr159261514792615355E0714680
chr159261587592615925E0715408
chr159261636292616751E0715895
chr159261677592616865E0716308
chr159261691892617000E0716451
chr159261702192617077E0716554
chr159261734092617413E0716873
chr159261746992617657E0717002
chr159261765892618341E0717191
chr159261838592618533E0717918
chr159261857792618657E0718110
chr159261877192618871E0718304
chr159261893792619443E0718470
chr159261959492619674E0719127
chr159261974992619799E0719282
chr159261990192620042E0719434
chr159262019892620307E0719731
chr159262032992620454E0719862
chr159262048192620992E07110014
chr159262106492621155E07110597
chr159262239692622596E07111929
chr159262266992622726E07112202
chr159262289192623116E07112424
chr159262319192623241E07112724
chr159262334492623404E07112877
chr159262510792625212E07114640
chr159262522192626027E07114754
chr159263317192633232E07122704
chr159263330892633393E07122841
chr159263353392633583E07123066
chr159263361192633651E07123144
chr159263365592633750E07123188
chr159263378292633832E07123315
chr159263431792634707E07123850
chr159263473792634942E07124270
chr159263497592635025E07124508
chr159263502792635138E07124560
chr159263517592635237E07124708
chr159263647292636711E07126005
chr159264057292641568E07130105
chr159264160592641655E07131138
chr159264169692641752E07131229
chr159264177292641825E07131305
chr159264187492642645E07131407
chr159264272392642773E07132256
chr159264528892645931E07134821
chr159264680992646863E07136342
chr159265147992651643E07141012
chr159265168592651802E07141218
chr159265184992652056E07141382
chr159265209792652255E07141630
chr159265242792652661E07141960
chr159265270392653499E07142236
chr159265351092653573E07143043
chr159265410592654290E07143638
chr159265437792655334E07143910
chr159265537992656091E07144912
chr159265629292656373E07145825
chr159265673892656788E07146271
chr159265682492656980E07146357
chr159265958992659847E07149122
chr159265994892660127E07149481
chr159266024792660324E07149780
chr159256066092561866E072-48601
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