rs7178747

Homo sapiens
T>A / T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T==0292 (8760/29926,GnomAD)
T==0409 (2048/5008,1000G)
T==0221 (852/3854,ALSPAC)
T==0223 (828/3708,TWINSUK)
chr15:81791436 (GRCh38.p7) (15q25.2)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.81791436T>A
GRCh38.p7 chr 15NC_000015.10:g.81791436T>G
GRCh37.p13 chr 15NC_000015.9:g.82083777T>A
GRCh37.p13 chr 15NC_000015.9:g.82083777T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.347G=0.648
1000GenomesAmericanSub694T=0.490G=0.51,
1000GenomesEast AsianSub1008T=0.719G=0.281
1000GenomesEuropeSub1006T=0.223G=0.777
1000GenomesGlobalStudy-wide5008T=0.409G=0.590
1000GenomesSouth AsianSub978T=0.300G=0.70,
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.221G=0.779
The Genome Aggregation DatabaseAfricanSub8714T=0.335G=0.662
The Genome Aggregation DatabaseAmericanSub838T=0.520G=0.48,
The Genome Aggregation DatabaseEast AsianSub1614T=0.757G=0.243
The Genome Aggregation DatabaseEuropeSub18458T=0.222G=0.777
The Genome Aggregation DatabaseGlobalStudy-wide29926T=0.292G=0.706
The Genome Aggregation DatabaseOtherSub302T=0.240G=0.76,
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.223G=0.777
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs71787470.000195alcohol consumption (maxi-drinks)24277619

eQTL of rs7178747 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7178747 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr153374585033745930E06730108
chr153374608433746181E06730342
chr153374634233746386E06730600
chr153371647733716527E068735
chr153374608433746181E06830342
chr153374634233746386E06830600
chr153374657133746682E06830829
chr153374884833748962E06833106
chr153376070933760823E06844967
chr153371713333717223E0691391
chr153366635033667142E070-48600
chr153366717833667306E070-48436
chr153368580933686354E070-29388
chr153368638133686475E070-29267
chr153368652633686619E070-29123
chr153368669633686888E070-28854
chr153368708233687197E070-28545
chr153368938833689481E070-26261
chr153368953033689580E070-26162
chr153368970933689807E070-25935
chr153369059033690737E070-25005
chr153369084433690922E070-24820
chr153371189733712482E070-3260
chr153372181933721879E0706077
chr153376070933760823E07144967
chr153376109733761258E07145355
chr153368580933686354E074-29388
chr153371713333717223E0741391
chr153371732533717681E0741583
chr153366609833666305E081-49437
chr153366635033667142E081-48600
chr153366717833667306E081-48436
chr153368638133686475E081-29267
chr153368652633686619E081-29123
chr153368669633686888E081-28854
chr153369059033690737E081-25005
chr153369084433690922E081-24820
chr153369107333691123E081-24619
chr153369456833695170E081-20572
chr153371154433711697E081-4045
chr153371189733712482E081-3260
chr153371271633712968E081-2774
chr153371304333713093E081-2649
chr153366590133665951E082-49791
chr153366609833666305E082-49437
chr153368938833689481E082-26261
chr153368953033689580E082-26162
chr153368970933689807E082-25935
chr153369059033690737E082-25005
chr153369084433690922E082-24820
chr153371074033710790E082-4952
chr153371271633712968E082-2774
chr153376070933760823E08244967
chr153376109733761258E08245355