rs7183893

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0218 (6535/29926,GnomAD)
C=0212 (6194/29118,TOPMED)
C=0156 (779/5008,1000G)
C=0304 (1171/3854,ALSPAC)
C=0297 (1103/3708,TWINSUK)
chr15:38704780 (GRCh38.p7) (15q14)
AD
GWASdb2
1   publication(s)
See rs on genome
7 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.38704780A>C
GRCh37.p13 chr 15NC_000015.9:g.38996981A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.905C=0.095
1000GenomesAmericanSub694A=0.750C=0.250
1000GenomesEast AsianSub1008A=0.967C=0.033
1000GenomesEuropeSub1006A=0.745C=0.255
1000GenomesGlobalStudy-wide5008A=0.844C=0.156
1000GenomesSouth AsianSub978A=0.800C=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.696C=0.304
The Genome Aggregation DatabaseAfricanSub8718A=0.868C=0.132
The Genome Aggregation DatabaseAmericanSub832A=0.760C=0.240
The Genome Aggregation DatabaseEast AsianSub1616A=0.972C=0.028
The Genome Aggregation DatabaseEuropeSub18460A=0.726C=0.273
The Genome Aggregation DatabaseGlobalStudy-wide29926A=0.781C=0.218
The Genome Aggregation DatabaseOtherSub300A=0.720C=0.280
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.787C=0.212
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.703C=0.297
PMID Title Author Journal
23089632A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.Wang JCMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs71838938.2E-07alcohol dependence23089632

eQTL of rs7183893 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7183893 in Fetal Brain

Probe ID Position Gene beta p-value
cg21039679chr15:38989738C15orf53-0.02661689197404671.7975e-14

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr153896065238961725E068-35256
chr153896065238961725E069-35256
chr153896065238961725E070-35256
chr153900002839001434E0813047
chr153900646639007349E0819485
chr153896051838960573E082-36408
chr153896065238961725E082-35256